SREK1 and SNRPD1

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SREK1	SNRPD1
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	small nuclear ribonucleoprotein D1 polypeptide 16kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	16 interactors: CLNS1A DDX20 GEMIN2 GEMIN4 GEMIN5 IL7R LSM3 LSM8 PRMT5 SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77
Entrez ID		140890	6632
HPRD ID		18043	03040
Ensembl ID		ENSG00000153914	ENSG00000167088
Uniprot IDs		E5RFV3 Q8WXA9	P62314
PDB IDs			1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	Spliceosomal SnRNP Assembly RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Cellular Macromolecular Complex Assembly RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Cellular Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Interleukin-7-mediated Signaling Pathway Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Metabolic Process RNA 3'-end Processing Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of T Cell Mediated Cytotoxicity Histone H4-R3 Methylation Endothelial Cell Activation Cellular Process Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Spliceosomal Tri-snRNP Complex Assembly Lymph Node Development
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