SREK1 and THRAP3

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SREK1	THRAP3
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	thyroid hormone receptor associated protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Mediator Complex Exon-exon Junction Complex Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Core Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Transcription Coactivator Activity Receptor Activity Protein Binding ATP Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding Phosphoprotein Binding
	Biological Process	MRNA Processing RNA Splicing	Regulation Of Alternative MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Transcription Initiation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Circadian Rhythm Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	6 interactors: APBB1 CSNK2A1 NEDD4 PIN1 SREK1 YWHAG
Entrez ID		140890	9967
HPRD ID		18043	07543
Ensembl ID		ENSG00000153914	ENSG00000054118
Uniprot IDs		E5RFV3 Q8WXA9	Q9Y2W1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	Regulation Of Cellular Component Organization Regulation Of Protein Metabolic Process Cell Cycle Regulation Of Neuron Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Negative Regulation Of Thymidylate Synthase Biosynthetic Process Development Involved In Symbiotic Interaction Generation Of Neurons Negative Regulation Of Cellular Response To Growth Factor Stimulus Neurogenesis Regulation Of Mitotic Nuclear Division Regulation Of Neurogenesis Neuron Projection Development Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Nervous System Development Neuron Development Positive Regulation Of Protein Catabolic Process Apoptotic Process Programmed Cell Death Progesterone Receptor Signaling Pathway Positive Regulation Of Intracellular Transport Cell Cycle Process Cell Death Death Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Regulation Of Cell Division Neuron Differentiation Cell Projection Organization Glucocorticoid Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Locomotion Signal Transduction Positive Regulation Of Signal Transduction Response To Light Stimulus Protein Targeting To Lysosome Regulation Of Cell Growth Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Signaling Protein Localization To Lysosome Signaling Axon Guidance Regulation Of Protein Catabolic Process
Tagcloud ?			aberrations applying arid2 axin1 cdk15 cps1 creating deleterious disruptions drive driver fn1 fusions genomes hccs hnf4a integrations intronic mll4 recurrently rps6ka3 seq silent splice tert transcriptomes transcriptomic tsc1 wgs
Tagcloud (Difference) ?			aberrations applying arid2 axin1 cdk15 cps1 creating deleterious disruptions drive driver fn1 fusions genomes hccs hnf4a integrations intronic mll4 recurrently rps6ka3 seq silent splice tert transcriptomes transcriptomic tsc1 wgs
Tagcloud (Intersection) ?