SREK1 and SH3GLB2

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (two hybrid)

		SREK1	SH3GLB2
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	SH3-domain GRB2-like endophilin B2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	8 interactors: CCDC158 GADD45G GIT2 KDM1A MAGEA1 SH3GLB1 SH3KBP1 SREK1
Entrez ID		140890	56904
HPRD ID		18043	15334
Ensembl ID		ENSG00000153914	ENSG00000148341
Uniprot IDs		E5RFV3 Q8WXA9	B7ZC38 Q9NR46
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	Regulation Of Primitive Erythrocyte Differentiation Regulation Of Signal Transduction Regulation Of Signaling Apoptotic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Programmed Cell Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Cell Death Death Negative Regulation Of Signal Transduction Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of P38MAPK Cascade Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Protein Oligomerization Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Behavioral Response To Pain Regulation Of Histone H3-K4 Methylation
Tagcloud ?			analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Difference) ?			analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Intersection) ?