SREK1 and TRA2B

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SREK1	TRA2B
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	transformer 2 beta homolog (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Nucleotide Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	26 interactors: CDK6 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 YTHDC1 YWHAG YWHAZ ZRANB2
Entrez ID		140890	6434
HPRD ID		18043	04097
Ensembl ID		ENSG00000153914
Uniprot IDs		E5RFV3 Q8WXA9	P62995
PDB IDs			2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing MRNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Localization Negative Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Gene Expression Termination Of RNA Polymerase II Transcription Cytoplasmic Transport RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Intracellular Transport RNA 3'-end Processing Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Cellular Localization Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Metabolic Process Metabolic Process
Tagcloud ?			3r 4r annonacin attractive brains characterised depending excess exists exon far intervene isoforms link microtubule mitochondrial neurodegenerative others palsy predominant prototypical psp repeat splicing srsf2 supranuclear tau upstream whilst
Tagcloud (Difference) ?			3r 4r annonacin attractive brains characterised depending excess exists exon far intervene isoforms link microtubule mitochondrial neurodegenerative others palsy predominant prototypical psp repeat splicing srsf2 supranuclear tau upstream whilst
Tagcloud (Intersection) ?