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SREK1 and HNRNPA2B1
Number of citations of the paper that reports this interaction (PMID
14559993
)
9
Data Source:
HPRD
(in vitro, two hybrid, in vivo)
SREK1
HNRNPA2B1
Gene Name
splicing regulatory glutamine/lysine-rich protein 1
heterogeneous nuclear ribonucleoprotein A2/B1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Membrane
Ribonucleoprotein Complex
Catalytic Step 2 Spliceosome
Molecular Function
Nucleotide Binding
Poly(A) RNA Binding
Nucleotide Binding
RNA Binding
Protein Binding
Single-stranded Telomeric DNA Binding
Poly(A) RNA Binding
Pre-mRNA Intronic Binding
Biological Process
MRNA Processing
RNA Splicing
Negative Regulation Of Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Negative Regulation Of MRNA Splicing, Via Spliceosome
RNA Transport
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
55 interactors:
CD8A
CSNK2A1
DDX17
DDX39B
DDX3X
DGKA
DGKD
EFTUD2
ELAVL1
GNB2L1
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPC
HNRNPD
HNRNPH1
HNRNPK
HNRNPU
ILF2
MDM2
NCL
NPM1
PABPC1
PABPC4
PARP1
PIN1
RBM10
RBMX
SAFB
SF3A3
SF3B3
SFPQ
SH3GLB2
SNRPD1
SNRPD3
SRPK1
SRPK2
SRPK3
SRSF1
SRSF10
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF8
SSRP1
SUPT16H
TARBP1
THRAP3
TRA2B
YBX1
ZRANB2
17 interactors:
CDKN2A
CSNK2A1
CSNK2B
ERG
HIPK3
HIST3H3
HNRNPL
LIG4
MAP4K2
NR4A1
PSMA3
SNRNP70
SREK1
TTF2
VHL
YAE1D1
ZMYM2
Entrez ID
140890
3181
HPRD ID
18043
02526
Ensembl ID
ENSG00000153914
ENSG00000122566
Uniprot IDs
E5RFV3
Q8WXA9
P22626
PDB IDs
1X4B
Enriched GO Terms of Interacting Partners
?
RNA Splicing
RNA Processing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of RNA Splicing
RNA Export From Nucleus
Termination Of RNA Polymerase II Transcription
RNA Transport
MRNA Export From Nucleus
RNA Localization
MRNA 3'-end Processing
Nuclear Export
MRNA Transport
Cellular Metabolic Process
RNA 3'-end Processing
DNA-templated Transcription, Termination
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Stability
Regulation Of RNA Stability
Nucleocytoplasmic Transport
Nuclear Transport
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
MRNA Stabilization
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Ribonucleoprotein Complex Biogenesis
Transcription, DNA-templated
Posttranscriptional Regulation Of Gene Expression
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Cytoplasmic Transport
Positive Regulation Of Cellular Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Gene Expression
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Apoptotic Process
Negative Regulation Of Cell Death
Programmed Cell Death
Regulation Of Cell Death
Cell Death
Death
RNA Splicing
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Catalytic Activity
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
MRNA Processing
Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Proliferation
Regulation Of Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity
MRNA Metabolic Process
Transcription, DNA-templated
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
RNA Processing
Regulation Of Catalytic Activity
Cellular Protein Modification Process
RNA Biosynthetic Process
DNA Ligation Involved In DNA Recombination
Negative Regulation Of Potassium Ion Export
Regulation Of Proteolysis
Regulation Of RNA Metabolic Process
Negative Regulation Of Ubiquitin-protein Transferase Activity
Phosphorylation
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Cellular Macromolecule Biosynthetic Process
Tagcloud
?
amyotrophic
autosomal
carriers
coding
conserved
equivocal
et
ewsr1
exons
export
familial
frontotemporal
fus
genotyped
genotyping
lobar
nes
neurodegeneration
pathogenicity
r471c
relatives
sequenced
subject
substitution
taf15
tardbp
tdp43
tremor
Tagcloud (Difference)
?
amyotrophic
autosomal
carriers
coding
conserved
equivocal
et
ewsr1
exons
export
familial
frontotemporal
fus
genotyped
genotyping
lobar
nes
neurodegeneration
pathogenicity
r471c
relatives
sequenced
subject
substitution
taf15
tardbp
tdp43
tremor
Tagcloud (Intersection)
?