SREK1 and SRSF10

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SREK1	SRSF10
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	serine/arginine-rich splicing factor 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding RS Domain Binding Unfolded Protein Binding
	Biological Process	MRNA Processing RNA Splicing	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated MRNA Splice Site Selection MRNA Export From Nucleus Cytoplasmic Transport Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	10 interactors: CSNK2A1 FUS SNRNP70 SREK1 SRSF1 SRSF4 TRA2A TRA2B YWHAB YWHAG
Entrez ID		140890	10772
HPRD ID		18043	05562
Ensembl ID		ENSG00000153914	ENSG00000188529
Uniprot IDs		E5RFV3 Q8WXA9	O75494
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Gene Expression RNA Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrion Organization MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Regulation Of Mitochondrion Organization RNA 3'-end Processing Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA 5'-splice Site Recognition Negative Regulation Of Protein Dephosphorylation Intracellular Transport Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Insulin Stimulus Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of RNA Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Organelle Organization Response To Insulin Regulation Of Cellular Protein Metabolic Process Apoptotic Process
Tagcloud ?			antigens autoregulatory b10 correlates deaf1 deformed drive hek293t hyperglycemia inflammation isoform lnscs lymph mediate nod nodes plns pta ptas ptbp2 s961 scid splenocytes spliced splicing stromal t1d tolerance var1
Tagcloud (Difference) ?			antigens autoregulatory b10 correlates deaf1 deformed drive hek293t hyperglycemia inflammation isoform lnscs lymph mediate nod nodes plns pta ptas ptbp2 s961 scid splenocytes spliced splicing stromal t1d tolerance var1
Tagcloud (Intersection) ?