Wiki-Pi
About
Search
People
Updates
Search
RACK1 and DYNLL1
Number of citations of the paper that reports this interaction (PubMedID
18420585
)
41
Data Source:
BioGRID
(pull down, biochemical)
RACK1
DYNLL1
Description
receptor for activated C kinase 1
dynein light chain LC8-type 1
Image
GO Annotations
Cellular Component
Phagocytic Cup
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Ribosome
Plasma Membrane
Small Ribosomal Subunit
Membrane
Cytosolic Small Ribosomal Subunit
Dendrite
Midbody
Cell Projection
Neuron Projection
Neuronal Cell Body
Perikaryon
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
IRE1-RACK1-PP2A Complex
Ribonucleoprotein Complex
Kinetochore
Nucleus
Chromosome
Cytoplasm
Mitochondrion
Centrosome
Cytosol
Cytoskeleton
Cytoplasmic Dynein Complex
Microtubule
Microtubule Associated Complex
Plasma Membrane
Cilium
COP9 Signalosome
Microtubule Cytoskeleton
Membrane
Secretory Granule
Dynein Complex
Site Of Double-strand Break
Tertiary Granule Membrane
Mitotic Spindle
Ciliary Tip
Ficolin-1-rich Granule Membrane
Axon Cytoplasm
Molecular Function
RNA Binding
Protein Kinase C Binding
Signaling Receptor Binding
Protein Binding
Enzyme Activator Activity
Ion Channel Inhibitor Activity
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Enzyme Binding
Protein Phosphatase Binding
Protein Serine/threonine Kinase Inhibitor Activity
Protein Tyrosine Kinase Inhibitor Activity
Cyclin Binding
Receptor Tyrosine Kinase Binding
Signaling Adaptor Activity
SH2 Domain Binding
Identical Protein Binding
Protein Homodimerization Activity
Ribosome Binding
Translation Regulator Activity
Cadherin Binding
BH3 Domain Binding
Molecular Adaptor Activity
Enzyme Inhibitor Activity
Protein Binding
Enzyme Binding
Nitric-oxide Synthase Regulator Activity
Nitric-oxide Synthase Inhibitor Activity
Identical Protein Binding
Protein-containing Complex Binding
Dynein Intermediate Chain Binding
Deoxyribonuclease Inhibitor Activity
Scaffold Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Cytoplasmic Translation
Translation
Regulation Of Translation
Apoptotic Process
Gastrulation
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Translation
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Localization
Positive Regulation Of Golgi To Plasma Membrane Protein Transport
Positive Regulation Of Apoptotic Process
Pigmentation
Positive Regulation Of GTPase Activity
Negative Regulation Of Smoothened Signaling Pathway
Rhythmic Process
Negative Regulation Of Phagocytosis
Regulation Of Cell Division
Regulation Of Cell Cycle
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Mitochondrial Depolarization
Cellular Response To Glucose Stimulus
Cellular Response To Growth Factor Stimulus
Rescue Of Stalled Ribosome
Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide
Regulation Of Establishment Of Cell Polarity
Positive Regulation Of Gastrulation
Negative Regulation Of Translational Frameshifting
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Apoptotic Process
DNA Damage Response
Microtubule-based Process
Spermatid Development
Substantia Nigra Development
Positive Regulation Of Intracellular Transport
Intraciliary Retrograde Transport
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Negative Regulation Of Phosphorylation
Motile Cilium Assembly
Negative Regulation Of Nitric Oxide Biosynthetic Process
DNA Strand Resection Involved In Replication Fork Processing
Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing
Pathways
Regulation of TNFR1 signaling
TNFR1-induced NF-kappa-B signaling pathway
TNFR1-mediated ceramide production
Degradation of CDH1
Activation of BIM and translocation to mitochondria
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Macroautophagy
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases Activate Formins
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
AURKA Activation by TPX2
HCMV Early Events
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Drugs
Copper
Diseases
GWAS
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
27863252
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Reading disability or specific language impairment (pleiotropy) (
25065397
)
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) (
25065397
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Interacting Genes
112 interacting genes:
ACTN2
ADH1B
ADRB2
AGTRAP
AR
ARRDC3
ATG14
ATG5
AURKB
BCL2L11
BECN1
BIRC6
BRCA1
CCNA1
CDKN1A
CHERP
CLEC1B
CNOT2
CRMP1
CSF2RB
DDX19B
DNM1
DYNLL1
EED
EIF6
ELOB
EP300
EPOR
ESR1
ESS2
FYN
GABRB3
GATA4
GGN
GNB1
GOLM1
GPBP1
GRAP2
GRIN2B
HABP4
HIF1A
HNRNPH2
IFNAR1
IFNAR2
IGF1R
IK
IL2RB
IL4R
IL7R
INSR
ITGB1
ITGB2
ITGB5
ITGB7
JAK1
KLHL20
LRP12
MAPK6
MCPH1
MKRN2
MTNR1A
NFATC1
NR3C1
NSMAF
OLA1
PABPC1
PDE4D
PIK3R4
PLCG1
PLEC
PRKAA1
PRKAB2
PRKAR2A
PRKCA
PRKCB
PRKCD
PRKCE
PRKD1
PRPF31
PTN
PTOV1
PTPRM
RASA1
RASA3
RB1
RHOA
SAT1
SLC27A6
SLC6A3
SLC9A5
SRC
SREK1
ST7
STAT1
STAT3
SUMO4
SYT1
TARDBP
TBXA2R
TENM1
TMEM131
TNFRSF1A
TP63
TP73
TSC22D4
TUBB
TUBG1
TYK2
USP40
USP54
WDR83
ZSCAN12
108 interacting genes:
ACTB
ACTC1
ACTG1
ALDOA
AMOTL2
B3GALT4
BACH1
BCAS1
BCL2L11
BMF
C14orf119
C19orf44
CA2
CACNB1
CCDC28A
CIMAP1A
CLIP2
COXFA4L2
CS
DAZ1
DCTN5
DLG4
DLGAP1
DNAJB9
DNM2
DNM3
DNMT1
DPPA3
DYNC1H1
DYNC1I1
DYRK1A
EEF1A1
ERG28
FAM153A
FAM53B
GABARAPL1
GABARAPL2
GAPDH
GLUD1
GLUL
GNL3L
GPHN
GPRIN2
GRIN3A
HIP1R
HMBOX1
HOMER3
HSPA8
IHO1
INPP1
IQUB
KANK2
LDHA
MAP1B
MARK3
MAST2
ME2
MORC3
MORN3
MRE11
MTA1
MTR
MYO10
MYO5A
NDEL1
NFKBIA
NOS1
NRF1
NTRK1
NTRK2
NTRK3
OR7C2
OTUD6A
PAK1
PAN2
PARD3
PAX6
PCM1
PFKM
PFKP
PKIA
PKIB
PKIG
POLH
PPP3R2
RAB4A
RACK1
RASGRP4
REDIC1
RGS2
SHROOM3
SLC13A1
SMCP
TERT
THAP10
THAP8
TNFRSF14
TP53BP1
TRIM54
TSNARE1
TUBA3C
TUBB
TXNDC17
VIM
ZHX1
ZMYND11
ZNF354A
ZNF710
Entrez ID
10399
8655
HPRD ID
01503
03334
Ensembl ID
ENSG00000204628
ENSG00000088986
Uniprot IDs
E9KL35
P63244
P63167
Q6FGH9
PDB IDs
4AOW
4UG0
4V5Z
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G18
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7NWH
7QP6
7QP7
7R4X
7TQL
7XNX
7XNY
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
1CMI
3ZKE
3ZKF
6GZJ
6GZL
6RLB
6SC2
7D35
8PR0
8PR1
8PTK
8RGG
Enriched GO Terms of Interacting Partners
?
Signal Transduction
Intracellular Signal Transduction
Cell Surface Receptor Signaling Pathway
Receptor Complex
Regulation Of Intracellular Signal Transduction
Protein Kinase Binding
Plasma Membrane
Positive Regulation Of Multicellular Organismal Process
Regulation Of Cell Communication
Regulation Of Signaling
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Protein Localization
Regulation Of Programmed Cell Death
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Developmental Process
Regulation Of Apoptotic Process
Regulation Of Signal Transduction
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Angiogenesis
Cell Surface Receptor Signaling Pathway Via STAT
Regulation Of Multicellular Organismal Process
Positive Regulation Of Vasculature Development
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Biological Quality
Intracellular Signaling Cassette
Cellular Response To Hormone Stimulus
Negative Regulation Of Apoptotic Process
Regulation Of Developmental Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Signal Transduction
Regulation Of Reactive Oxygen Species Metabolic Process
Transcription Corepressor Binding
Phosphorylation
Developmental Process
Enzyme Binding
Positive Regulation Of Cellular Component Organization
Identical Protein Binding
Regulation Of Glycolytic Process
Protein Phosphorylation
Cytoplasm
Diacylglycerol-dependent Serine/threonine Kinase Activity
Positive Regulation Of Transport
Regulation Of Protein Localization
Negative Regulation Of Intracellular Signal Transduction
Response To Hormone
Cytoskeleton
Microtubule
Cytoplasm
Postsynaptic Density
Microtubule Binding
Neurotrophin Receptor Activity
Neurotrophin Binding
Cytosol
Pyruvate Metabolic Process
Neuron Projection Morphogenesis
Nucleotide Binding
Cell Projection Morphogenesis
Glycolytic Process
Fructose 1,6-bisphosphate Metabolic Process
Cytoskeleton Organization
Actin Filament
Identical Protein Binding
ADP Catabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Microtubule-based Process
Apical Junction Complex
ADP Metabolic Process
Nucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Positive Regulation Of Cellular Component Biogenesis
Replication Fork
CAMP-dependent Protein Kinase Inhibitor Activity
Cytoskeleton-dependent Intracellular Transport
Dendritic Spine
Organelle Organization
Axon
Establishment Of Organelle Localization
Axonogenesis
Microtubule Associated Complex
Carbohydrate Catabolic Process
Peptidyl-cysteine S-nitrosylase Activity
6-phosphofructokinase Activity
6-phosphofructokinase Complex
Beta-tubulin Binding
Ribonucleoside Diphosphate Metabolic Process
Purine Ribonucleotide Catabolic Process
Microtubule Cytoskeleton Organization
Substantia Nigra Development
Negative Regulation Of Protein Import Into Nucleus
Myelination In Peripheral Nervous System
Regulation Of Transport
Nucleoside Diphosphate Metabolic Process
Regulation Of Transepithelial Transport
Calyx Of Held
Fructose-6-phosphate Binding
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?