COL4A1 and HABP2

Number of citations of the paper that reports this interaction (PMID 1724753)
9

Data Source:
HPRD (in vivo)

		COL4A1	HABP2
Gene Name		collagen, type IV, alpha 1	hyaluronan binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix	Extracellular Region Extracellular Space
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Platelet-derived Growth Factor Binding	Serine-type Endopeptidase Activity Glycosaminoglycan Binding
	Biological Process	Patterning Of Blood Vessels Receptor-mediated Endocytosis Axon Guidance Brain Development Neuromuscular Junction Development Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Epithelial Cell Differentiation Blood Vessel Morphogenesis Retinal Blood Vessel Morphogenesis Renal Tubule Morphogenesis Cellular Response To Amino Acid Stimulus Basement Membrane Organization	Proteolysis Cell Adhesion
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Arterial stiffness ( 20031579) Coronary heart disease ( 21378990) Obesity-related traits ( 23251661)
Protein-Protein Interactions		27 interactors: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1	7 interactors: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 KNG1
Entrez ID		1282	3026
HPRD ID		00359	04890
Ensembl ID		ENSG00000187498	ENSG00000148702
Uniprot IDs		P02462	Q14520
PDB IDs		1LI1
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Response To Wounding Wound Healing Acute-phase Response Extracellular Matrix Disassembly Tissue Development Blood Coagulation Platelet Degranulation Hemostasis Acute Inflammatory Response Multicellular Organismal Development System Development Cell Adhesion Anatomical Structure Development Locomotion Platelet Activation Response To Stress Endodermal Cell Differentiation Regulation Of Body Fluid Levels Developmental Process Formation Of Primary Germ Layer Regulation Of Wound Healing Inflammatory Response Endoderm Formation Anatomical Structure Morphogenesis Negative Regulation Of Platelet Activation Negative Regulation Of Wound Healing Organ Development Defense Response Negative Regulation Of Phosphatidylinositol Biosynthetic Process Gastrulation Cell Migration Movement Of Cell Or Subcellular Component Endoderm Development Chemotaxis Positive Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Cell Differentiation Regulation Of Blood Coagulation Regulation Of Platelet Activation Cell Motility Response To Stimulus Leukocyte Migration Connective Tissue Development Blood Vessel Morphogenesis Negative Regulation Of Phospholipid Biosynthetic Process Cell Activation Immune System Process Regulation Of Protein Metabolic Process	Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Catabolic Process Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Glomerular Basement Membrane Development Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Cell Development Response To External Stimulus Renal System Development Neuromuscular Junction Development Urogenital System Development Glomerulus Development Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Angiogenesis Nephron Development Endothelial Cell Apoptotic Process Cell Differentiation Synapse Organization Retinal Blood Vessel Morphogenesis Regulation Of Angiogenesis Negative Regulation Of Endopeptidase Activity System Development Negative Regulation Of Peptidase Activity Kidney Development Blood Circulation Positive Regulation Of Renal Sodium Excretion Retina Vasculature Morphogenesis In Camera-type Eye Angiogenesis
Tagcloud ?		arteriopathy autosomal cadasil cavitary confirms eif2b encountered entity excluded fifty frequencies heterogeneous increasingly infancy infarcts inherited leukoencephalopathies leukoencephalopathy magnetic matter onset oriented realized resonance subcortical symmetrical systematic underestimated white
Tagcloud (Difference) ?		arteriopathy autosomal cadasil cavitary confirms eif2b encountered entity excluded fifty frequencies heterogeneous increasingly infancy infarcts inherited leukoencephalopathies leukoencephalopathy magnetic matter onset oriented realized resonance subcortical symmetrical systematic underestimated white
Tagcloud (Intersection) ?