COL4A1 and MATN2

  • Number of citations: 23 (PubMedID 12180907)
  • Data Source: HPRD (in vivo)

COL4A1

MATN2

Name collagen type IV alpha 1 chain matrilin 2
Structure PDB 1LI1 No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways None
Diseases None
GWAS
  • Age-related nuclear cataracts ( 24951543 )
  • Arterial stiffness ( 20031579 )
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833 )
  • Coronary artery disease ( 32469254 33020668 24262325 26343387 29212778 )
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975 )
  • Coronary heart disease ( 21378990 )
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133 )
  • Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136 )
  • Hip circumference adjusted for BMI ( 34021172 )
  • Hip index ( 34021172 )
  • Intraocular pressure ( 31959993 29785010 )
  • Lateral ventricle volume ( 31530798 )
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 )
  • Lymphocyte count ( 32888494 )
  • Mean platelet volume ( 32888494 )
  • Metabolite levels ( 23823483 )
  • Monocyte count ( 32888494 27863252 )
  • Myocardial infarction ( 33532862 26343387 )
  • Night sleep phenotypes ( 27126917 )
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377 )
  • Obesity-related traits ( 23251661 )
  • Peripheral artery disease ( 31285632 )
  • Platelet count ( 32888494 )
  • Platelet distribution width ( 32888494 )
  • Plateletcrit ( 32888494 )
  • Pulse pressure ( 30578418 )
  • Stroke ( 30383316 )
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993 )
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993 )
  • Waist-hip index ( 34021172 )
  • Waist-to-hip ratio adjusted for BMI ( 28552196 34021172 )
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065 )
  • Diffusing capacity of carbon monoxide ( 30694715 )
  • Eosinophilic esophagitis ( 34506852 )
  • Erectile dysfunction ( 30583798 )
Novel Interactors 1 novel interactors: CXCR4 None recorded
Interacting Genes 30 interacting genes: ACHE APCS APP BGN BMP3 CD93 COL18A1 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI TGM2 THBS1 17 interacting genes: ATXN1 ATXN1L ATXN7 CACNA1A CBFA2T3 COL1A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 DVL3 FBN2 FN1 MATN1 MATN4
Entrez ID 1282 4147
HPRD ID 00359 03660
Ensembl ID ENSG00000187498 ENSG00000132561
Uniprot IDs A5PKV2 P02462 A0A140VKH7 O00339 Q8N2G3
PDB IDs 1LI1 5NAX 5NAY 6MPX Not available
GO Terms Enriched among Interactors