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TRIM28 and YWHAQ
Number of citations of the paper that reports this interaction (PMID
15161933
)
63
Data Source:
BioGRID
(pull down)
TRIM28
YWHAQ
Gene Name
tripartite motif containing 28
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Euchromatin
Nuclear Heterochromatin
RNA Polymerase II Transcription Factor Complex
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Cytoplasmic Vesicle Membrane
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Kinase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Krueppel-associated Box Domain Binding
Sequence-specific DNA Binding
Poly(A) RNA Binding
Chromo Shadow Domain Binding
Protein Binding
Protein Domain Specific Binding
Protein N-terminus Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Epithelial To Mesenchymal Transition
DNA Repair
Transcription Initiation From RNA Polymerase II Promoter
Embryo Implantation
Gene Expression
Protein Ubiquitination
Protein Sumoylation
Positive Regulation Of Transcription Factor Import Into Nucleus
DNA Methylation Involved In Embryo Development
Innate Immune Response
Positive Regulation Of DNA Repair
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Protein Autophosphorylation
Protein Oligomerization
Convergent Extension Involved In Axis Elongation
Embryonic Placenta Morphogenesis
Negative Regulation Of DNA Demethylation
Negative Regulation Of Viral Release From Host Cell
Regulation Of Genetic Imprinting
Protein Targeting
Apoptotic Process
Small GTPase Mediated Signal Transduction
Substantia Nigra Development
Negative Regulation Of Transcription, DNA-templated
Membrane Organization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Generic Transcription Pathway
Activation of BAD and translocation to mitochondria
Programmed Cell Death
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Heart rate variability traits (
22174390
)
Protein-Protein Interactions
62 interactors:
CBX1
CBX3
CBX5
CDC34
CDCA4
CEBPB
CHAF1A
CHD3
ESR1
FES
HDAC10
HTRA2
IRF1
IRF7
LYN
MAGEA2
MAGEA2B
MAGEA3
MAGEA6
MAGED1
MYB
NDNL2
NR3C1
NR4A1
NR4A3
PFDN5
PPP4C
RNF4
SENP7
SERTAD1
SERTAD2
SETDB1
SIN3A
SKI
SMARCAD1
SPG7
STAT3
TRIM24
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2H
UBE2I
UBE2L3
UBE2N
UBE2U
VHL
VIM
YWHAQ
ZNF10
ZNF133
ZNF140
ZNF197
ZNF354A
ZNF382
ZNF420
ZNF496
ZNF689
ZNF74
231 interactors:
AARS2
ABL1
ACSL4
AHCY
AKT1S1
ANXA1
ANXA2
APC
AR
ARHGAP10
ARHGEF16
ATP5A1
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDK17
CDK18
CDKN1A
CDKN1B
CEP170
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
EXO1
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1L1
HADHA
HAT1
HAX1
HDAC4
HDAC5
HDAC7
HIST1H2BG
HIST2H4A
HNRNPA1
HNRNPC
HNRNPF
HNRNPH1
HNRNPK
HSPA1A
HSPA8
HUS1
IARS2
ING1
IQGAP1
IRS2
ITGB4
KCNK15
KCNK3
KCNK9
KIAA1429
KIF1C
KIF23
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LMO7
LYST
MAGOH
MAP3K3
MAP3K5
MARK2
MARK3
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPC4
PABPN1
PAK4
PANK1
PCM1
PDCD6
PDE3A
PDE3B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C2B
PIK3C3
PIK3CB
PKM
PPFIBP1
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
PTPN3
RAF1
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSFA2
SSX2IP
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TP53BP2
TPI1
TPR
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS
WDR61
WDR77
WEE1
WTAP
WWC2
WWP1
YAP1
YWHAE
YWHAG
ZC3H13
ZHX2
Entrez ID
10155
10971
HPRD ID
03445
00886
Ensembl ID
ENSG00000130726
ENSG00000134308
Uniprot IDs
Q13263
B4DMT8
P27348
PDB IDs
1FP0
2RO1
2YVR
2BTP
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Protein K48-linked Ubiquitination
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Protein Polyubiquitination
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Protein Catabolic Process
Cellular Metabolic Process
Regulation Of Cellular Process
Cellular Protein Catabolic Process
Positive Regulation Of Metabolic Process
Protein Ubiquitination
Biosynthetic Process
Protein Modification By Small Protein Conjugation
Protein K11-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Ubiquitin-protein Transferase Activity
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Metabolic Process
Organelle Organization
Cellular Process
Cellular Response To Organic Substance
Regulation Of Cellular Component Organization
Response To Organic Substance
Response To Stimulus
Positive Regulation Of Cellular Metabolic Process
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Mitotic Cell Cycle
Regulation Of Metabolic Process
Response To Stress
Cell Cycle
Cellular Response To Stimulus
Mitotic Cell Cycle Process
Death
Regulation Of Apoptotic Process
Programmed Cell Death
Regulation Of Protein Localization
Intracellular Signal Transduction
Apoptotic Process
Cell Cycle Process
Anatomical Structure Development
Cell Death
Regulation Of Cellular Localization
System Development
Multicellular Organismal Development
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Regulation Of Cell Cycle
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Abiotic Stimulus
Positive Regulation Of Protein Metabolic Process
Intracellular Transport
Regulation Of Signaling
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Regulation Of Phosphorylation
Innate Immune Response
MRNA Metabolic Process
Cellular Localization
Immune System Process
Regulation Of Kinase Activity
Tagcloud
?
accumulates
aging
becoming
damaged
depletion
genomes
il6
il8
ink4a
insults
kap1
knocked
krab
limits
mediating
mixture
ois
oncogene
partially
pathologies
prevented
profound
reinforcing
sasp
secrete
secretory
senescence
termed
undergo
Tagcloud (Difference)
?
accumulates
aging
becoming
damaged
depletion
genomes
il6
il8
ink4a
insults
kap1
knocked
krab
limits
mediating
mixture
ois
oncogene
partially
pathologies
prevented
profound
reinforcing
sasp
secrete
secretory
senescence
termed
undergo
Tagcloud (Intersection)
?