BAZ1B and HIST2H2AC

Number of citations of the paper that reports this interaction (PMID 16252006)
31

Data Source:
BioGRID (pull down)

		BAZ1B	HIST2H2AC
Gene Name		bromodomain adjacent to zinc finger domain, 1B	histone cluster 2, H2ac
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Pericentric Heterochromatin Nuclear Replication Fork	Nucleosome Nucleus Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Lysine-acetylated Histone Binding Vitamin D Receptor Activator Activity	Molecular_function DNA Binding Protein Heterodimerization Activity
	Biological Process	Heart Morphogenesis Double-strand Break Repair Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Receptor Activity	Biological_process
Pathways			RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323) Protein C levels ( 20802025) Triglycerides ( 20864672) Urate levels ( 23263486)
Protein-Protein Interactions		15 interactors: CDT1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MAPK14 MAPK3 MAPK9 MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1	65 interactors: ANP32A ATXN7L3 BAP1 BARD1 BAZ1B BMI1 BRCA1 CDY1 CHFR COPRS CRP CTCFL CTDP1 DDB2 DNMT3L EIF2AK2 EP300 GATAD2A GATAD2B HAT1 HDAC2 HIST1H2BA HIST1H3A HIST1H4A HIST2H2BE HIST2H4A KAT2A KAT2B KAT5 KAT7 MSL2 MYSM1 NAP1L4 NCAPH NCL NPM1 PARP10 PBRM1 PELP1 PRMT5 PRMT7 RAG1 RBBP4 RCC1 RNF168 RNF2 RNF20 RNF8 SART3 SIRT7 SSRP1 TAF15 TAF1A TAF1B TCF20 TSPY1 TSSK6 UBC UBE2B UBR2 UIMC1 USP12 USP16 USP22 USP46
Entrez ID		9031	8338
HPRD ID		10416	09107
Ensembl ID		ENSG00000009954	ENSG00000184260
Uniprot IDs		Q9UIG0	Q16777
PDB IDs		1F62
Enriched GO Terms of Interacting Partners?		Nucleosome Organization ATP-dependent Chromatin Remodeling Chromatin Assembly Or Disassembly Chromosome Organization Chromatin Remodeling Chromatin Organization Chromatin Silencing At RDNA Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleosome Assembly Chromatin Silencing Chromatin Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Protein-DNA Complex Assembly DNA Packaging Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic DNA Replication-dependent Nucleosome Assembly Toll-like Receptor 4 Signaling Pathway DNA Conformation Change Chromatin Modification DNA Metabolic Process DNA Methylation On Cytosine Gene Silencing Nucleosome Disassembly Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Nitrogen Compound Metabolic Process Response To Stress Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Activation Of Innate Immune Response	Chromatin Organization Chromosome Organization Chromatin Modification Histone Modification Organelle Organization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Histone Ubiquitination Regulation Of Gene Expression, Epigenetic Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process DNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Cellular Protein Metabolic Process Gene Expression Chromatin Remodeling Regulation Of Metabolic Process Chromatin Silencing Cellular Metabolic Process DNA Packaging Nucleosome Organization Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Chromatin Assembly Or Disassembly Negative Regulation Of Nucleic Acid-templated Transcription Histone H2A Ubiquitination Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Histone Acetylation Nucleosome Assembly RNA Metabolic Process Protein-DNA Complex Assembly Internal Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Negative Regulation Of Biosynthetic Process Cell Cycle Histone Deubiquitination Chromatin Assembly
Tagcloud ?		ac accessible architecture attenuates clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv
Tagcloud (Difference) ?		ac accessible architecture attenuates clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv
Tagcloud (Intersection) ?