BAZ1B and NR4A2

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		BAZ1B	NR4A2
Gene Name		bromodomain adjacent to zinc finger domain, 1B	nuclear receptor subfamily 4, group A, member 2
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Pericentric Heterochromatin Nuclear Replication Fork	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Chromatin Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Lysine-acetylated Histone Binding Vitamin D Receptor Activator Activity	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Heterodimerization Activity
	Biological Process	Heart Morphogenesis Double-strand Break Repair Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Receptor Activity	Response To Hypoxia Neuron Migration Response To Amphetamine Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Adult Locomotory Behavior Post-embryonic Development Response To Inorganic Substance Gene Expression Death Response To Insecticide Central Nervous System Projection Neuron Axonogenesis Habenula Development Intracellular Receptor Signaling Pathway Cellular Response To Extracellular Stimulus Cellular Response To Oxidative Stress Regulation Of Dopamine Metabolic Process Dopamine Biosynthetic Process Neuron Maturation Positive Regulation Of Catalytic Activity Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Transcription From RNA Polymerase II Promoter General Adaptation Syndrome Dopaminergic Neuron Differentiation
Pathways			Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323) Protein C levels ( 20802025) Triglycerides ( 20864672) Urate levels ( 23263486)	Menarche (age at onset) ( 21102462) Response to statin therapy ( 20339536)
Protein-Protein Interactions		15 interactors: CDT1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MAPK14 MAPK3 MAPK9 MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1	15 interactors: BAZ1B CDKN1C CDKN2D COPS5 PIAS4 PPARG RARA RARB RPS6KA1 RXRA RXRB SMARCA2 SMARCA4 TCEAL5 VHL
Entrez ID		9031	4929
HPRD ID		10416	03493
Ensembl ID		ENSG00000009954	ENSG00000153234
Uniprot IDs		Q9UIG0	F1D8N6 F5H4G9 P43354 Q53EL4 Q6NXU0
PDB IDs		1F62	1OVL
Enriched GO Terms of Interacting Partners?		Nucleosome Organization ATP-dependent Chromatin Remodeling Chromatin Assembly Or Disassembly Chromosome Organization Chromatin Remodeling Chromatin Organization Chromatin Silencing At RDNA Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleosome Assembly Chromatin Silencing Chromatin Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Protein-DNA Complex Assembly DNA Packaging Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic DNA Replication-dependent Nucleosome Assembly Toll-like Receptor 4 Signaling Pathway DNA Conformation Change Chromatin Modification DNA Metabolic Process DNA Methylation On Cytosine Gene Silencing Nucleosome Disassembly Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Nitrogen Compound Metabolic Process Response To Stress Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Activation Of Innate Immune Response	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Retinoic Acid Receptor Signaling Pathway Ventricular Cardiac Muscle Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Steroid Hormone Mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Response To Retinoic Acid RNA Biosynthetic Process Heart Development Transcription From RNA Polymerase II Promoter Cardiovascular System Development Hormone-mediated Signaling Pathway Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Muscle Cell Differentiation Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Cellular Response To Steroid Hormone Stimulus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cell Proliferation Intracellular Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Heart Morphogenesis DNA-templated Transcription, Initiation RNA Metabolic Process Muscle Structure Development Aortic Smooth Muscle Cell Differentiation Nitrogen Compound Metabolic Process Gene Expression
Tagcloud ?		ac accessible architecture attenuates clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv	519d allograft artificial attenuate bac c19mc cxcl6 decidua evt evts extravillous feto foxl2 immunological indirectly invade microrna mirna mirnas myometrium naturally placenta placental trophoblast trophoblasts undifferentiated utr villous vts
Tagcloud (Difference) ?		ac accessible architecture attenuates clarify cytoprotective foci gammah2ax h2ax h3k56 h3k9 hubs integrated ints3 irradiation isoform mark matrix mount prevents proteomic respond runx runx2 ruvbl2 scaffolding subnuclear supported uv	519d allograft artificial attenuate bac c19mc cxcl6 decidua evt evts extravillous feto foxl2 immunological indirectly invade microrna mirna mirnas myometrium naturally placenta placental trophoblast trophoblasts undifferentiated utr villous vts
Tagcloud (Intersection) ?