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F11R and PTPRB
Number of citations of the paper that reports this interaction (PMID
12234928
)
54
Data Source:
HPRD
(in vivo)
F11R
PTPRB
Gene Name
F11 receptor
protein tyrosine phosphatase, receptor type, B
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Tight Junction
Microtubule Cytoskeleton
Integral Component Of Membrane
Cell Junction
Cytoplasmic Vesicle
Slit Diaphragm
Extracellular Vesicular Exosome
Integral Component Of Plasma Membrane
Receptor Complex
Molecular Function
Protein Binding
PDZ Domain Binding
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Biological Process
Inflammatory Response
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Blood Coagulation
Response To Radiation
Viral Process
Extracellular Matrix Organization
Actomyosin Structure Organization
Positive Regulation Of Rap GTPase Activity
Negative Regulation Of Rho GTPase Activity
Cell Junction Assembly
Cell-cell Junction Organization
Positive Regulation Of Blood Pressure
Intestinal Absorption
Leukocyte Migration
Tight Junction Assembly
Establishment Of Protein Localization To Plasma Membrane
Establishment Of Endothelial Intestinal Barrier
Regulation Of Membrane Permeability
Regulation Of Actin Cytoskeleton Reorganization
Angiogenesis
Protein Dephosphorylation
Phosphate-containing Compound Metabolic Process
Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Pathways
Loss of Function of TGFBR2 in Cancer
Cell junction organization
TGFBR2 MSI Frameshift Mutants in Cancer
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Tight junction interactions
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Cell surface interactions at the vascular wall
Cell-cell junction organization
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Integrin cell surface interactions
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
16 interactors:
ASIP
BDNF
CASK
CGN
CSNK2A1
F2RL2
ITGAL
MLLT4
MPDZ
PARD3
PEX19
PICK1
PRKCA
PTPRB
SGTA
TJP1
10 interactors:
CDH5
CNTN1
CNTNAP1
F11R
GHR
MAGI3
MET
NRCAM
TEK
TNC
Entrez ID
50848
5787
HPRD ID
12038
01474
Ensembl ID
ENSG00000158769
ENSG00000127329
Uniprot IDs
B7Z941
Q6FIB4
Q9Y624
B7ZKS8
F5H3G6
P23467
Q86VA4
PDB IDs
1NBQ
3EOY
3TSZ
2AHS
2H02
2H03
2H04
2HC1
2HC2
2I3R
2I3U
2I4E
2I4G
2I4H
2I5X
Enriched GO Terms of Interacting Partners
?
Cell Junction Assembly
Cell-cell Junction Organization
Cell-cell Junction Assembly
Establishment Of Endothelial Intestinal Barrier
Signal Transduction
Epithelial Cell Development
Membrane Organization
Cell-cell Signaling
Signaling
Cell Communication
Anatomical Structure Development
Protein Localization To Membrane
Cell Development
Cellular Response To Stimulus
Developmental Process
Establishment Of Endothelial Barrier
Epithelial Cell Differentiation
Cell Surface Receptor Signaling Pathway
Endothelial Cell Development
Tight Junction Assembly
Regulation Of Body Fluid Levels
Cellular Response To Growth Factor Stimulus
Epithelial Cell Morphogenesis
Epithelium Development
Anatomical Structure Morphogenesis
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Wound Healing
Response To Growth Factor
Receptor Clustering
Tissue Development
G-protein Coupled Receptor Signaling Pathway
Cell-cell Signaling Involved In Cell-cell Junction Organization
Response To Anesthetic
Negative Regulation Of Lipid Binding
Positive Regulation Of Dense Core Granule Biogenesis
Response To Fluoxetine
Response To L-glutamate
Cell Differentiation
Cell Adhesion
Chaperone-mediated Protein Folding
Negative Regulation Of Synaptic Transmission
Cellular Response To Organic Substance
Response To Wounding
Response To Stimulus
Locomotion
Apical Junction Assembly
Cell Morphogenesis Involved In Differentiation
Endothelial Cell Differentiation
Cellular Response To Carbohydrate Stimulus
Multicellular Organismal Development
Cell Adhesion
Signaling
Cell Communication
Cell Development
Axon Development
Locomotion
Neuronal Action Potential Propagation
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Movement Of Cell Or Subcellular Component
Axon Guidance
Mesenchymal-epithelial Cell Signaling
Enzyme Linked Receptor Protein Signaling Pathway
Neuron Development
Positive Regulation Of MAPK Cascade
Response To Stimulus
Positive Regulation Of Kinase Activity
Cell Morphogenesis
Axonogenesis
Neuron Differentiation
Cell Projection Organization
Positive Regulation Of Transferase Activity
Cell Junction Assembly
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Cellular Response To Stimulus
Cell-cell Junction Organization
Positive Regulation Of MAP Kinase Activity
Regulation Of MAPK Cascade
Positive Regulation Of Signal Transduction
Neuron Projection Morphogenesis
Anatomical Structure Development
Cell Differentiation
Positive Regulation Of Metabolic Process
Regulation Of Establishment Or Maintenance Of Cell Polarity
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Actin Cytoskeleton Reorganization
Positive Regulation Of Protein Phosphorylation
Anatomical Structure Morphogenesis
Signal Transduction
Endothelial Cell Development
Positive Regulation Of Protein Serine/threonine Kinase Activity
Peptidyl-tyrosine Phosphorylation
Regulation Of MAP Kinase Activity
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Generation Of Neurons
Developmental Process
Positive Regulation Of Intracellular Signal Transduction
Transmission Of Nerve Impulse
Tagcloud
?
accumulative
acknowledged
astrocytoma
chi3l1
chr1
chr22
clustering
crocc
daughter
discover
ecm
exome
gbm
hereditary
lymphatic
multiforme
narrow
pilocytic
players
pms2
pontine
predisposition
proximity
q12
siblings
snvs
striking
synonymous
underline
Tagcloud (Difference)
?
accumulative
acknowledged
astrocytoma
chi3l1
chr1
chr22
clustering
crocc
daughter
discover
ecm
exome
gbm
hereditary
lymphatic
multiforme
narrow
pilocytic
players
pms2
pontine
predisposition
proximity
q12
siblings
snvs
striking
synonymous
underline
Tagcloud (Intersection)
?