Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
F11R and ASIP
Number of citations of the paper that reports this interaction (PMID
11447115
)
69
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
F11R
ASIP
Gene Name
F11 receptor
agouti signaling protein
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Tight Junction
Microtubule Cytoskeleton
Integral Component Of Membrane
Cell Junction
Cytoplasmic Vesicle
Slit Diaphragm
Extracellular Vesicular Exosome
Extracellular Space
Molecular Function
Protein Binding
PDZ Domain Binding
Receptor Binding
Type 3 Melanocortin Receptor Binding
Type 4 Melanocortin Receptor Binding
Biological Process
Inflammatory Response
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Blood Coagulation
Response To Radiation
Viral Process
Extracellular Matrix Organization
Actomyosin Structure Organization
Positive Regulation Of Rap GTPase Activity
Negative Regulation Of Rho GTPase Activity
Cell Junction Assembly
Cell-cell Junction Organization
Positive Regulation Of Blood Pressure
Intestinal Absorption
Leukocyte Migration
Tight Junction Assembly
Establishment Of Protein Localization To Plasma Membrane
Establishment Of Endothelial Intestinal Barrier
Regulation Of Membrane Permeability
Regulation Of Actin Cytoskeleton Reorganization
Generation Of Precursor Metabolites And Energy
Signal Transduction
Cell-cell Signaling
Adult Feeding Behavior
Hormone-mediated Signaling Pathway
Melanosome Transport
Melanosome Organization
Regulation Of Molecular Function, Epigenetic
Melanin Biosynthetic Process
Genetic Imprinting
Pathways
Loss of Function of TGFBR2 in Cancer
Cell junction organization
TGFBR2 MSI Frameshift Mutants in Cancer
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Tight junction interactions
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Cell surface interactions at the vascular wall
Cell-cell junction organization
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Integrin cell surface interactions
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Breast cancer (
22976474
)
Burning and freckling (
18488028
)
Freckles (
18488028
)
Freckling (
20585627
)
Hair color (
20585627
)
Melanoma (
21983787
)
Red vs. non-red hair color (
18488028
)
Skin sensitivity to sun (
18488028
)
Tanning (
23548203
)
Protein-Protein Interactions
16 interactors:
ASIP
BDNF
CASK
CGN
CSNK2A1
F2RL2
ITGAL
MLLT4
MPDZ
PARD3
PEX19
PICK1
PRKCA
PTPRB
SGTA
TJP1
6 interactors:
F11R
MC1R
MC2R
MC3R
MC4R
MC5R
Entrez ID
50848
434
HPRD ID
12038
02562
Ensembl ID
ENSG00000158769
ENSG00000101440
Uniprot IDs
B7Z941
Q6FIB4
Q9Y624
P42127
PDB IDs
1NBQ
3EOY
3TSZ
1Y7J
1Y7K
2IQW
2KZA
2L1J
Enriched GO Terms of Interacting Partners
?
Cell Junction Assembly
Cell-cell Junction Organization
Cell-cell Junction Assembly
Establishment Of Endothelial Intestinal Barrier
Signal Transduction
Epithelial Cell Development
Membrane Organization
Cell-cell Signaling
Signaling
Cell Communication
Anatomical Structure Development
Protein Localization To Membrane
Cell Development
Cellular Response To Stimulus
Developmental Process
Establishment Of Endothelial Barrier
Epithelial Cell Differentiation
Cell Surface Receptor Signaling Pathway
Endothelial Cell Development
Tight Junction Assembly
Regulation Of Body Fluid Levels
Cellular Response To Growth Factor Stimulus
Epithelial Cell Morphogenesis
Epithelium Development
Anatomical Structure Morphogenesis
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Wound Healing
Response To Growth Factor
Receptor Clustering
Tissue Development
G-protein Coupled Receptor Signaling Pathway
Cell-cell Signaling Involved In Cell-cell Junction Organization
Response To Anesthetic
Negative Regulation Of Lipid Binding
Positive Regulation Of Dense Core Granule Biogenesis
Response To Fluoxetine
Response To L-glutamate
Cell Differentiation
Cell Adhesion
Chaperone-mediated Protein Folding
Negative Regulation Of Synaptic Transmission
Cellular Response To Organic Substance
Response To Wounding
Response To Stimulus
Locomotion
Apical Junction Assembly
Cell Morphogenesis Involved In Differentiation
Endothelial Cell Differentiation
Cellular Response To Carbohydrate Stimulus
Multicellular Organismal Development
Positive Regulation Of CAMP Biosynthetic Process
Positive Regulation Of CAMP Metabolic Process
Positive Regulation Of Cyclic Nucleotide Metabolic Process
Regulation Of CAMP Biosynthetic Process
Regulation Of CAMP Metabolic Process
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
G-protein Coupled Receptor Signaling Pathway
Regulation Of Feeding Behavior
Regulation Of Phosphorus Metabolic Process
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Signal Transduction
Signaling
Cell Communication
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Cellular Response To Stimulus
Homoiothermy
Regulation Of Blood Pressure
Regulation Of Behavior
Positive Regulation Of Feeding Behavior
Regulation Of Metabolic Process
Positive Regulation Of Protein Kinase A Signaling
UV-damage Excision Repair
Establishment Of Endothelial Intestinal Barrier
Diet Induced Thermogenesis
Negative Regulation Of Feeding Behavior
Response To Stimulus
Regulation Of Grooming Behavior
Regulation Of Nitrogen Compound Metabolic Process
Blood Circulation
Positive Regulation Of Protein Kinase C Signaling
Negative Regulation Of Rho GTPase Activity
UV Protection
Positive Regulation Of Bone Resorption
Regulation Of Protein Kinase A Signaling
Positive Regulation Of Rap GTPase Activity
Regulation Of Protein Kinase C Signaling
Response To Dietary Excess
Melanin Biosynthetic Process
Melanin Metabolic Process
Negative Regulation Of Ras GTPase Activity
Response To Radiation
Regulation Of Rap GTPase Activity
Secondary Metabolite Biosynthetic Process
Intestinal Absorption
Sodium Ion Homeostasis
Temperature Homeostasis
Regulation Of Rap Protein Signal Transduction
Tagcloud
?
agouti
albinism
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
prkar1a
prkar2a
prkar2b
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Difference)
?
agouti
albinism
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
prkar1a
prkar2a
prkar2b
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Intersection)
?