F11R and MLLT4

Number of citations of the paper that reports this interaction (PMID 10856295)
63

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		F11R	MLLT4
Gene Name		F11 receptor	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Slit Diaphragm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Cell Junction Apical Part Of Cell
	Molecular Function	Protein Binding PDZ Domain Binding	Protein Binding Protein C-terminus Binding Ras GTPase Binding Cell Adhesion Molecule Binding
	Biological Process	Inflammatory Response Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Blood Coagulation Response To Radiation Viral Process Extracellular Matrix Organization Actomyosin Structure Organization Positive Regulation Of Rap GTPase Activity Negative Regulation Of Rho GTPase Activity Cell Junction Assembly Cell-cell Junction Organization Positive Regulation Of Blood Pressure Intestinal Absorption Leukocyte Migration Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Regulation Of Actin Cytoskeleton Reorganization	Cell Adhesion Signal Transduction Cell-cell Signaling Positive Regulation Of Rap GTPase Activity Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier
Pathways		Loss of Function of TGFBR2 in Cancer Cell junction organization TGFBR2 MSI Frameshift Mutants in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer Tight junction interactions Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Cell surface interactions at the vascular wall Cell-cell junction organization Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer Integrin cell surface interactions SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Metabolite levels (5-HIAA) ( 23319000)
Protein-Protein Interactions		16 interactors: ASIP BDNF CASK CGN CSNK2A1 F2RL2 ITGAL MLLT4 MPDZ PARD3 PEX19 PICK1 PRKCA PTPRB SGTA TJP1	37 interactors: BCR CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NRXN1 NRXN2 NRXN3 PFN1 PICK1 PVRL1 PVRL2 PVRL3 PVRL4 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG
Entrez ID		50848	4301
HPRD ID		12038	01164
Ensembl ID		ENSG00000158769	ENSG00000130396
Uniprot IDs		B7Z941 Q6FIB4 Q9Y624	P55196
PDB IDs		1NBQ 3EOY 3TSZ	1T2M 1XZ9 2AIN 2EXG
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Cell-cell Junction Assembly Establishment Of Endothelial Intestinal Barrier Signal Transduction Epithelial Cell Development Membrane Organization Cell-cell Signaling Signaling Cell Communication Anatomical Structure Development Protein Localization To Membrane Cell Development Cellular Response To Stimulus Developmental Process Establishment Of Endothelial Barrier Epithelial Cell Differentiation Cell Surface Receptor Signaling Pathway Endothelial Cell Development Tight Junction Assembly Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Epithelial Cell Morphogenesis Epithelium Development Anatomical Structure Morphogenesis Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Wound Healing Response To Growth Factor Receptor Clustering Tissue Development G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Anesthetic Negative Regulation Of Lipid Binding Positive Regulation Of Dense Core Granule Biogenesis Response To Fluoxetine Response To L-glutamate Cell Differentiation Cell Adhesion Chaperone-mediated Protein Folding Negative Regulation Of Synaptic Transmission Cellular Response To Organic Substance Response To Wounding Response To Stimulus Locomotion Apical Junction Assembly Cell Morphogenesis Involved In Differentiation Endothelial Cell Differentiation Cellular Response To Carbohydrate Stimulus Multicellular Organismal Development	Signaling Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Anatomical Structure Development Developmental Process Cell Development Cell Projection Organization Signal Transduction Nervous System Development Axon Development Cellular Response To Stimulus Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Response To Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Axonogenesis Cell Part Morphogenesis System Development Cell Differentiation Neuron Differentiation Ras Protein Signal Transduction Multicellular Organismal Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Neuron Projection Development Neuron Projection Morphogenesis Locomotion Cell Projection Morphogenesis Regulation Of Signaling Cell Junction Assembly Cell Morphogenesis Involved In Differentiation Cell-cell Junction Organization Regulation Of Cellular Component Organization Cell Adhesion Chemotaxis Small GTPase Mediated Signal Transduction Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To External Stimulus Adherens Junction Organization Cellular Component Assembly Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Signal Transduction Regulation Of Synapse Assembly Cellular Response To Organic Substance Response To Organic Substance Learning
Tagcloud ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Difference) ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Intersection) ?