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ZNF512B and VHL
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
ZNF512B
VHL
Gene Name
zinc finger protein 512B
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
Mitochondrion
Endoplasmic Reticulum
Cytosol
Membrane
Intermediate Filament Cytoskeleton
Molecular Function
DNA Binding
Metal Ion Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Ubiquitin Protein Ligase Activity
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
Regulation Of Transcription, DNA-templated
Proteolysis
Negative Regulation Of Cell Proliferation
Protein Ubiquitination
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Protein Stabilization
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hypoxia
Pathways
Cellular response to hypoxia
Antigen processing: Ubiquitination & Proteasome degradation
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
60 interactors:
ANKLE2
ANKRD28
AP1G1
APLP2
ATRX
BRD1
BTBD2
CDC123
CREBZF
CTBP2
DCTN1
DDX3X
DROSHA
DVL3
EHMT2
FAM129B
FHL3
GLRX3
HEYL
HTATSF1
IL36RN
INVS
KDM2A
KDM3B
KLF10
KMT2B
L1TD1
LAMB2
LZTS2
MBD1
MYH10
OS9
PAPPA2
PBRM1
PDE4DIP
PEG10
PIAS4
PLCG2
PPP1R15A
PTPRF
RPS27A
SDF4
SIAH1
SMAD1
SPTBN1
SUPT5H
TGM2
TNKS2
TOM1
TOX4
TRAF1
TRAF4
VHL
VPS35
VPS41
VWF
XPC
XRCC6
YES1
ZMYM2
85 interactors:
ACTB
APP
AR
AURKA
CAPN7
CAPZB
CBR1
CBX1
CBX3
CCT3
CD44
CDC34
CHEK2
CLU
CSNK2A1
CUL2
CUL5
DGKI
DNAJA3
DVL2
E2F1
EEF1B2
EPAS1
FKBP8
FLNA
FN1
HDAC1
HDAC2
HDAC3
HIF1A
HIF1AN
HIF3A
HIST1H1C
HIST1H2BL
HIST4H4
HNRNPA2B1
HNRNPD
HSPA5
HSPA8
JADE1
KIF2C
KIF3A
KLF4
LANCL1
MDFI
NCL
NR4A1
NR4A2
NR4A3
PDCD5
PLD1
POLR2G
PRDX1
PRKCD
PRKCI
PRMT1
PRMT8
PSMC3
RB1CC1
RBPMS
RBPMS2
RBX1
RNF139
RPL21
RPL5
RPS15A
SARNP
SAT2
SKP2
SLC2A1
SLC3A2
SON
SP1
TCEB1
TCEB2
TRIM28
UBE2D1
USP20
USP33
UXT
VAPB
VBP1
YY1AP1
ZNF197
ZNF512B
Entrez ID
57473
7428
HPRD ID
13840
01905
Ensembl ID
ENSG00000196700
Uniprot IDs
Q96KM6
P40337
PDB IDs
2GQJ
1LM8
1LQB
1VCB
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Process
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organ Development
System Development
Transcription, DNA-templated
Developmental Process
Chromosome Organization
Anatomical Structure Development
Regulation Of Gene Expression
RNA Biosynthetic Process
Response To Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Chromatin Modification
Negative Regulation Of Biosynthetic Process
Cell Cycle
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cell Cycle Process
Multicellular Organismal Development
Viral Genome Replication
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin Organization
Wnt Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Cell Surface Receptor Signaling Pathway
Organelle Organization
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Chromatin Remodeling
RNA Metabolic Process
Primary MiRNA Processing
Vesicle-mediated Transport
Endosomal Transport
Regulation Of Signal Transduction
Cellular Response To Stress
Mitotic Cell Cycle Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Gene Expression
Response To Stress
Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Response To Stress
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Gene Expression
Cellular Metabolic Process
RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Metabolic Process
Cellular Response To Stress
Positive Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Cellular Response To Oxygen Levels
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cell Death
Nitrogen Compound Metabolic Process
Positive Regulation Of Protein Metabolic Process
Blood Coagulation
Positive Regulation Of Cellular Protein Metabolic Process
Hemostasis
Heterocycle Metabolic Process
Positive Regulation Of Gene Expression
Cellular Aromatic Compound Metabolic Process
Regulation Of Apoptotic Process
Regulation Of Protein Metabolic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Body Fluid Levels
Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Wound Healing
Regulation Of Signal Transduction
Response To Stimulus
Tagcloud
?
ankyrin
attenuates
bc
belonging
binds
box
collection
degenerate
elongation
elongin
hippel
inhibiting
initially
interacting
jak
lindau
motif
multifunctional
multiprotein
participates
pol
repeat
skp1
socs
spry
stat
suppressor
von
wd
Tagcloud (Difference)
?
ankyrin
attenuates
bc
belonging
binds
box
collection
degenerate
elongation
elongin
hippel
inhibiting
initially
interacting
jak
lindau
motif
multifunctional
multiprotein
participates
pol
repeat
skp1
socs
spry
stat
suppressor
von
wd
Tagcloud (Intersection)
?