ZNF512B and APLP2

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		ZNF512B	APLP2
Gene Name		zinc finger protein 512B	amyloid beta (A4) precursor-like protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Metal Ion Binding	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Suckling Behavior Cellular Copper Ion Homeostasis Regulation Of Epidermal Growth Factor-activated Receptor Activity G-protein Coupled Receptor Signaling Pathway Mating Behavior Locomotory Behavior Cholesterol Metabolic Process Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Forebrain Development Midbrain Development Regulation Of Protein Binding Neuromuscular Process Controlling Balance
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	23 interactors: ADIPOR1 AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 VKORC1 ZNF512B
Entrez ID		57473	334
HPRD ID		13840	00103
Ensembl ID		ENSG00000196700	ENSG00000084234
Uniprot IDs		Q96KM6	B4E3I5 Q06481
PDB IDs		2GQJ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Response To Radiation Negative Regulation Of Cell Death Cellular Response To Organic Substance Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Response To Growth Factor Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Response To Organic Substance Apoptotic Process Response To Cytokine Signal Transduction Programmed Cell Death Response To External Stimulus Cell Death Response To Stimulus Death Positive Regulation Of Metabolic Process Response To Stress Intracellular Signal Transduction Response To Abiotic Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Signaling Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Cell Communication Regulation Of Transcription, DNA-templated Apoptotic Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Leading Edge Cell Differentiation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Immune System Process Regulation Of Growth Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of RNA Metabolic Process Regulation Of Cell Adhesion Regulation Of Immune System Process Neurotrophin TRK Receptor Signaling Pathway Response To Hormone
Tagcloud ?			allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological
Tagcloud (Difference) ?			allowed app backgroundamyloid conclusionsthe cooperative fertility interacting interactome male members modules motility network networks ontologyand oocyte outside playing reproduction reproductive resultswe screen shed specified sperm spermatozoa superfamily testis topological
Tagcloud (Intersection) ?