ZNF512B and PBRM1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		ZNF512B	PBRM1
Gene Name		zinc finger protein 512B	polybromo 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromosome Kinetochore
	Molecular Function	DNA Binding Metal Ion Binding	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Placenta Development Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitotic Nuclear Division Heart Development Negative Regulation Of Cell Proliferation
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Bipolar disorder ( 21926972) Bipolar disorder (mood-incongruent) ( 23092984) Major mood disorders ( 20081856)
Protein-Protein Interactions		60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	9 interactors: APP HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE PTS SMARCA4 ZDHHC17 ZNF512B
Entrez ID		57473	55193
HPRD ID		13840	07302
Ensembl ID		ENSG00000196700	ENSG00000163939
Uniprot IDs		Q96KM6	Q86U86
PDB IDs		2GQJ	2KTB 3G0J 3HMF 3IU5 3IU6 3K2J 3LJW 3MB4 3TLP
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter	DNA Methylation On Cytosine Nucleosome Organization Chromatin Assembly Or Disassembly Chromatin Silencing DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification DNA Replication-dependent Nucleosome Assembly Gene Silencing Nucleosome Assembly Chromatin Assembly Chromatin Silencing At RDNA Protein-DNA Complex Assembly DNA Packaging Regulation Of Gene Expression, Epigenetic Chromatin Organization DNA Conformation Change ATP-dependent Chromatin Remodeling Chromosome Organization Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Histone H4-K20 Demethylation Cellular Macromolecular Complex Assembly DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Megakaryocyte Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Chromatin Remodeling Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Axon Choice Point Recognition Tetrahydrobiopterin Biosynthetic Process Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Regulation Of Mitotic Cell Cycle Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Cycle Phase Transition Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Remodeling Cellular Component Assembly Positive Regulation By Host Of Viral Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of Binding Central Nervous System Development Developmental Growth
Tagcloud ?			1000x abstracted arid1a bap1 cca cdkn2a cholangiocarcinoma entities extrahepatic fbxw7 fgfr gas hiseq hotspot idh1 illumina indolent intrahepatic introns kras mcl1 ngs pgm presentations radiologic sequencer smad4 targetable worse
Tagcloud (Difference) ?			1000x abstracted arid1a bap1 cca cdkn2a cholangiocarcinoma entities extrahepatic fbxw7 fgfr gas hiseq hotspot idh1 illumina indolent intrahepatic introns kras mcl1 ngs pgm presentations radiologic sequencer smad4 targetable worse
Tagcloud (Intersection) ?