VHL and EPAS1

  • Number of citations of the paper that reports this interaction (PMID 10823831)
  • 161
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

VHL

EPAS1

Gene Name von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase endothelial PAS domain protein 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 85 interactors: ACTB APP AR AURKA CAPN7 CAPZB CBR1 CBX1 CBX3 CCT3 CD44 CDC34 CHEK2 CLU CSNK2A1 CUL2 CUL5 DGKI DNAJA3 DVL2 E2F1 EEF1B2 EPAS1 FKBP8 FLNA FN1 HDAC1 HDAC2 HDAC3 HIF1A HIF1AN HIF3A HIST1H1C HIST1H2BL HIST4H4 HNRNPA2B1 HNRNPD HSPA5 HSPA8 JADE1 KIF2C KIF3A KLF4 LANCL1 MDFI NCL NR4A1 NR4A2 NR4A3 PDCD5 PLD1 POLR2G PRDX1 PRKCD PRKCI PRMT1 PRMT8 PSMC3 RB1CC1 RBPMS RBPMS2 RBX1 RNF139 RPL21 RPL5 RPS15A SARNP SAT2 SKP2 SLC2A1 SLC3A2 SON SP1 TCEB1 TCEB2 TRIM28 UBE2D1 USP20 USP33 UXT VAPB VBP1 YY1AP1 ZNF197 ZNF512B 32 interactors: APC ARNT ARNT2 ARNTL ARNTL2 BATF BATF2 BATF3 BBS1 BBS2 BBS4 DBP DDIT3 EGLN1 EGLN2 EGLN3 EIF3E EP300 EWSR1 F12 HSP90AA1 JUN KLHL20 MAX MEF2C NDN PRKD1 SMAD3 SPP1 STAT5A TERF2IP VHL
Entrez ID 7428 2034
HPRD ID 01905 06787
Ensembl ID ENSG00000116016
Uniprot IDs P40337 B3KW07 Q99814
PDB IDs 1LM8 1LQB 1VCB 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 1P97 2A24 3F1N 3F1O 3F1P 3H7W 3H82 4GHI 4GS9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ankyrin  attenuates  bc  belonging  binds  box  collection  degenerate  elongation  elongin  hippel  inhibiting  initially  interacting  jak  lindau  motif  multifunctional  multiprotein  participates  pol  repeat  skp1  socs  spry  stat  suppressor  von  wd 
2alpha  adaptation  adapted  altitude  another  approaches  basis  concert  egln1  encodes  hif  hif2a  humans  hydroxylase  hypoxia  inducible  locations  offer  orchestrates  phd2  populations  prolyl  regulators  signatures  tibetans  toward  treating  unraveling  wide 
Tagcloud (Difference) ?
ankyrin  attenuates  bc  belonging  binds  box  collection  degenerate  elongation  elongin  hippel  inhibiting  initially  interacting  jak  lindau  motif  multifunctional  multiprotein  participates  pol  repeat  skp1  socs  spry  stat  suppressor  von  wd 
2alpha  adaptation  adapted  altitude  another  approaches  basis  concert  egln1  encodes  hif  hif2a  humans  hydroxylase  hypoxia  inducible  locations  offer  orchestrates  phd2  populations  prolyl  regulators  signatures  tibetans  toward  treating  unraveling  wide 
Tagcloud (Intersection) ?