ZNF512B and IL36RN

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		ZNF512B	IL36RN
Gene Name		zinc finger protein 512B	interleukin 36 receptor antagonist
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Extracellular Space
	Molecular Function	DNA Binding Metal Ion Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Cytokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Negative Regulation Of Interferon-gamma Secretion
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	7 interactors: MCM6 REL SKIL SSBP2 SSBP3 SSBP4 ZNF512B
Entrez ID		57473	26525
HPRD ID		13840	16112
Ensembl ID		ENSG00000196700	ENSG00000136695
Uniprot IDs		Q96KM6	Q9UBH0
PDB IDs		2GQJ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter	Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Anterior Head Development Neural Plate Anterior/posterior Regionalization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Protein Heterotrimerization Midbrain-hindbrain Boundary Development Nitrogen Compound Metabolic Process DNA Unwinding Involved In DNA Replication RNA Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Protein Homotrimerization Rostrocaudal Neural Tube Patterning Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors DNA Strand Elongation Involved In DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter DNA Strand Elongation Lens Fiber Cell Differentiation DNA Replication Initiation Protein Trimerization Blastocyst Formation Head Morphogenesis NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-12 Production Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Immune System Process Response To Cytokine Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Chordate Embryonic Development Body Morphogenesis
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