VHL and DVL2

  • Number of citations of the paper that reports this interaction (PMID 20639871)
  • 57
  • Data Source:
  • BioGRID (enzymatic study)

VHL

DVL2

Gene Name von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase dishevelled segment polarity protein 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 85 interactors: ACTB APP AR AURKA CAPN7 CAPZB CBR1 CBX1 CBX3 CCT3 CD44 CDC34 CHEK2 CLU CSNK2A1 CUL2 CUL5 DGKI DNAJA3 DVL2 E2F1 EEF1B2 EPAS1 FKBP8 FLNA FN1 HDAC1 HDAC2 HDAC3 HIF1A HIF1AN HIF3A HIST1H1C HIST1H2BL HIST4H4 HNRNPA2B1 HNRNPD HSPA5 HSPA8 JADE1 KIF2C KIF3A KLF4 LANCL1 MDFI NCL NR4A1 NR4A2 NR4A3 PDCD5 PLD1 POLR2G PRDX1 PRKCD PRKCI PRMT1 PRMT8 PSMC3 RB1CC1 RBPMS RBPMS2 RBX1 RNF139 RPL21 RPL5 RPS15A SARNP SAT2 SKP2 SLC2A1 SLC3A2 SON SP1 TCEB1 TCEB2 TRIM28 UBE2D1 USP20 USP33 UXT VAPB VBP1 YY1AP1 ZNF197 ZNF512B 61 interactors: AP1M1 AP2M1 ARHGEF39 ARR3 ARRB1 ARRB2 ATN1 AXIN1 BAG3 BAHD1 CCDC33 CPSF7 CSNK1E CTBP2 DAAM1 DDI1 DPPA2 DYNLT1 ENKD1 FZD4 GABARAP GABARAPL1 ITCH LRRK2 MAP1LC3A MCRS1 OTULIN PARD6A PCBD1 PLA2G12A POLI PPM1A PRKCA PRKCB PRKCG PRPF3 RAC1 RBFOX1 RBPMS RHOA RHOXF2 RNF185 RNPS1 RUNX2 SMURF1 SNF8 SNIP1 SORBS3 TCEB3B THAP1 TIFA TP53 TRAF2 U2AF2 USP5 VANGL1 VHL ZBTB8A ZNF165 ZNF250 ZNF263
Entrez ID 7428 1856
HPRD ID 01905 03690
Ensembl ID ENSG00000004975
Uniprot IDs P40337 I3L2N2 O14641
PDB IDs 1LM8 1LQB 1VCB 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 2REY 3CBX 3CBY 3CBZ 3CC0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ankyrin  attenuates  bc  belonging  binds  box  collection  degenerate  elongation  elongin  hippel  inhibiting  initially  interacting  jak  lindau  motif  multifunctional  multiprotein  participates  pol  repeat  skp1  socs  spry  stat  suppressor  von  wd 
adaptor  ap2  ap2mu2  assembled  assembles  blockage  clathrin  clustering  continuously  disassembled  dissolution  endocytic  endocytosis  follows  fz  inhibiton  internalization  lrp6  maintain  mu2  path  rab  routes  signalosome  take  transducer  transducers  vertebrates  wnt 
Tagcloud (Difference) ?
ankyrin  attenuates  bc  belonging  binds  box  collection  degenerate  elongation  elongin  hippel  inhibiting  initially  interacting  jak  lindau  motif  multifunctional  multiprotein  participates  pol  repeat  skp1  socs  spry  stat  suppressor  von  wd 
adaptor  ap2  ap2mu2  assembled  assembles  blockage  clathrin  clustering  continuously  disassembled  dissolution  endocytic  endocytosis  follows  fz  inhibiton  internalization  lrp6  maintain  mu2  path  rab  routes  signalosome  take  transducer  transducers  vertebrates  wnt 
Tagcloud (Intersection) ?