ZNF512B and KMT2B

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		ZNF512B	KMT2B
Gene Name		zinc finger protein 512B	lysine (K)-specific methyltransferase 2B
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Histone Methyltransferase Complex
	Molecular Function	DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Ovarian Follicle Development Chromatin Organization Transcription, DNA-templated Oocyte Differentiation Gene Silencing Ovulation Chromatin-mediated Maintenance Of Transcription Histone H3-K4 Methylation Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	22 interactors: ANXA1 ANXA7 ATP1B1 ATXN1 CDKN1A GRB7 HIST1H3A HIST2H3C NREP PIN1 PRPF40A RAP1B RCC1 RPP14 SEPT8 SMAD3 SMARCB1 SMN1 TK1 TSC22D1 WDR5 ZNF512B
Entrez ID		57473	9757
HPRD ID		13840	06017
Ensembl ID		ENSG00000196700	ENSG00000272333
Uniprot IDs		Q96KM6	Q9UMN6
PDB IDs		2GQJ	3UVM 4ERZ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter	Hemostasis Response To Wounding Regulation Of Body Fluid Levels Response To Stress Wound Healing Regulation Of Mitotic Cell Cycle Blood Coagulation Nucleobase-containing Compound Metabolic Process DNA Methylation On Cytosine Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Cycle Process Regulation Of Metabolic Process Chromatin Silencing At RDNA Cellular Nitrogen Compound Metabolic Process Epithelial Cell Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Organic Cyclic Compound Gene Silencing Negative Regulation Of Gene Expression Cell Cycle Regulation Of Cell Cycle Regulation Of Cellular Component Organization Digestive Tract Development Nitrogen Compound Metabolic Process Digestive System Development Response To Abiotic Stimulus Liver Development Response To X-ray Response To Glucocorticoid Positive Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Phosphorylation Gene Expression Response To Corticosteroid Chromatin Silencing Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Gene Expression, Epigenetic Neutrophil Clearance Positive Regulation Of Transforming Growth Factor Beta3 Production Fetal Process Involved In Parturition Regulation Of Cell Junction Assembly RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cytokinesis DNA Methylation Cellular Process Regulation Of Cell Division RNA Processing Mitotic Cell Cycle Phase Transition
Tagcloud ?			alters associates demethylase h3k4 h3k4me3 hmt hyperplastic igf2bp2 integrative interactive islet islets jarid1 jumonji kdm5a kmt2a landscape men1 menin methyltransferases mll1 mll4 neuroendocrine pancreatic pannets rbp2 seq trimethylation unbiased
Tagcloud (Difference) ?			alters associates demethylase h3k4 h3k4me3 hmt hyperplastic igf2bp2 integrative interactive islet islets jarid1 jumonji kdm5a kmt2a landscape men1 menin methyltransferases mll1 mll4 neuroendocrine pancreatic pannets rbp2 seq trimethylation unbiased
Tagcloud (Intersection) ?