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PAK7 and SORBS3
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PAK7
SORBS3
Gene Name
p21 protein (Cdc42/Rac)-activated kinase 7
sorbin and SH3 domain containing 3
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Molecular Function
Receptor Signaling Protein Serine/threonine Kinase Activity
ATP Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
Biological Process
Mitotic Cell Cycle
Protein Phosphorylation
Apoptotic Process
Cytoskeleton Organization
Signal Transduction
Learning
Memory
Locomotory Behavior
Cell Proliferation
Cell Growth
Cell Migration
Signal Transduction By Phosphorylation
Intracellular Signal Transduction
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Pathways
Axon guidance
Activation of Rac
Signaling by Robo receptor
Smooth Muscle Contraction
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
HIV-1 control (
20205591
)
Protein-Protein Interactions
20 interactors:
ARMC7
ATPAF2
BAD
CARD9
CCNG1
CDC42
CRBN
EMD
EXOSC1
FAM212A
FHL3
GCC1
LENG1
LZTS2
PDLIM7
PSMF1
RAC1
SORBS3
TUBGCP4
UXT
46 interactors:
ABL1
ADAM15
ADAMTSL4
AKT1
ARNT2
CBLB
CPNE2
CPSF7
DDX17
DIP2A
DLG5
DMRTB1
DVL2
EFS
EIF3H
FAM154A
FASLG
FLOT1
HNRNPK
HNRNPUL1
INPPL1
KIAA0408
KIAA1217
MAPK1
MAPK3
NCKIPSD
NOTCH3
PAK1
PAK2
PAK7
RBMX
SAFB2
SH2D4A
SOCS7
SRCIN1
TBC1D22B
TRIM23
TRIM27
TRIM41
VARS2
VPS37B
VPS37C
ZBED1
ZBTB25
ZBTB7B
ZC4H2
Entrez ID
57144
10174
HPRD ID
06423
11535
Ensembl ID
ENSG00000101349
ENSG00000120896
Uniprot IDs
B0AZM9
Q9P286
O60504
PDB IDs
2F57
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
?
Cytoskeleton Organization
Organelle Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
Cellular Protein Complex Assembly
Mitotic Cell Cycle Process
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Mitotic Cell Cycle
Positive Regulation Of Signal Transduction
Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Phosphorylation
Immune Response-regulating Signaling Pathway
Positive Regulation Of Phosphorylation
Positive Regulation Of T Cell Activation
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Apoptotic Process
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Actin Filament Bundle Assembly
Regulation Of Phosphorus Metabolic Process
Regulation Of Signal Transduction
Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of Intracellular Transport
Positive Regulation Of Transferase Activity
Cellular Response To Chromate
Organelle Transport Along Microtubule
Positive Regulation Of Cell-cell Adhesion
Regulation Of Cell Death
Protein Complex Assembly
Regulation Of Lipid Kinase Activity
Cell Cycle Process
Fc Receptor Signaling Pathway
Regulation Of Stress Fiber Assembly
Wnt Signaling Pathway
Positive Regulation Of DNA Replication
Cellular Macromolecular Complex Assembly
Regulation Of Signaling
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Actin Filament Organization
Positive Regulation Of Neuron Death
Regulation Of Wnt Signaling Pathway
Positive Regulation Of Mitochondrial Membrane Potential
Embryonic Olfactory Bulb Interneuron Precursor Migration
Negative Regulation Of Interleukin-23 Production
Positive Regulation Of Hair Follicle Cell Proliferation
Suppression By Virus Of Host Apoptotic Process
T Cell Costimulation
Gene Expression
Regulation Of Cellular Amino Acid Metabolic Process
Transcription, DNA-templated
Regulation Of Cellular Ketone Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Fc Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Biosynthetic Process
Regulation Of Gene Expression
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Innate Immune Response
Response To Insulin
Immune Response
Regulation Of Protein Phosphorylation
Negative Regulation Of Transferase Activity
Response To Epidermal Growth Factor
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Golgi Inheritance
Negative Regulation Of Protein Phosphorylation
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Caveolin-mediated Endocytosis
Cellular Response To Insulin Stimulus
Cell Morphogenesis Involved In Differentiation
Protein Autophosphorylation
Positive Regulation Of Protein Phosphorylation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Phosphorus Metabolic Process
Tagcloud
?
10a
200c
30a
30c
arhgap5
cd36
cdh2
cdk5r1
chips
cyp27b1
figure
gemcitabine
gna13
gp5
hist1h2bf
hlf
igsf3
ikbkb
il32
intriguing
mirs
nrp2
oxidoreductase
putatively
rab23
rap2a
slc11a1
sod3
tp53i3
Tagcloud (Difference)
?
10a
200c
30a
30c
arhgap5
cd36
cdh2
cdk5r1
chips
cyp27b1
figure
gemcitabine
gna13
gp5
hist1h2bf
hlf
igsf3
ikbkb
il32
intriguing
mirs
nrp2
oxidoreductase
putatively
rab23
rap2a
slc11a1
sod3
tp53i3
Tagcloud (Intersection)
?