PAK7 and TUBGCP4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		PAK7	TUBGCP4
Gene Name		p21 protein (Cdc42/Rac)-activated kinase 7	tubulin, gamma complex associated protein 4
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Spindle Pole Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	Receptor Signaling Protein Serine/threonine Kinase Activity ATP Binding	Structural Constituent Of Cytoskeleton
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Proliferation Cell Growth Cell Migration Signal Transduction By Phosphorylation Intracellular Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Complex Assembly Microtubule Nucleation
Pathways		Axon guidance Activation of Rac Signaling by Robo receptor	G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FAM212A FHL3 GCC1 LENG1 LZTS2 PDLIM7 PSMF1 RAC1 SORBS3 TUBGCP4 UXT	26 interactors: ADAMTSL4 AP2B1 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 LZTR1 MAD1L1 NUDT3 OBFC1 PAK7 RNF146 RPRD1B SDSL SPERT TRIM27 TUBG1 USHBP1 VIM
Entrez ID		57144	27229
HPRD ID		06423	10616
Ensembl ID		ENSG00000101349	ENSG00000137822
Uniprot IDs		B0AZM9 Q9P286	Q9UGJ1
PDB IDs		2F57	3RIP
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Organelle Organization Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Assembly Mitotic Cell Cycle Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Mitotic Cell Cycle Positive Regulation Of Signal Transduction Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Transferase Activity Cellular Response To Chromate Organelle Transport Along Microtubule Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Death Protein Complex Assembly Regulation Of Lipid Kinase Activity Cell Cycle Process Fc Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Wnt Signaling Pathway Positive Regulation Of DNA Replication Cellular Macromolecular Complex Assembly Regulation Of Signaling Regulation Of T Cell Activation Positive Regulation Of Cell Activation Actin Filament Organization Positive Regulation Of Neuron Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Potential Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Suppression By Virus Of Host Apoptotic Process T Cell Costimulation	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Cytoskeleton Organization Golgi To Plasma Membrane Transport Astrocyte Differentiation Diphosphoinositol Polyphosphate Catabolic Process Regulation Of Metaphase Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Schwann Cell Proliferation Organelle Organization Negative Regulation Of Interleukin-2 Secretion
Tagcloud ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Difference) ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Intersection) ?