PAK7 and LENG1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PAK7	LENG1
Gene Name		p21 protein (Cdc42/Rac)-activated kinase 7	leukocyte receptor cluster (LRC) member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Cellular_component
	Molecular Function	Receptor Signaling Protein Serine/threonine Kinase Activity ATP Binding	Molecular_function
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Proliferation Cell Growth Cell Migration Signal Transduction By Phosphorylation Intracellular Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Biological_process
Pathways		Axon guidance Activation of Rac Signaling by Robo receptor
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FAM212A FHL3 GCC1 LENG1 LZTS2 PDLIM7 PSMF1 RAC1 SORBS3 TUBGCP4 UXT	36 interactors: APP BANP CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC57 CDR2 CEP57L1 CEP70 FSD2 GOLGA2 KIFC3 KLF10 KRT31 KRT40 LDOC1 MID2 MTUS2 NAB2 NAGK NECAB2 OSGEP PAK7 PDE4DIP PNMA1 ROPN1 SPERT STX11 TCF4 TFIP11 TMEM239 TRIM27 TRIM54 USHBP1
Entrez ID		57144	79165
HPRD ID		06423	13985
Ensembl ID		ENSG00000101349
Uniprot IDs		B0AZM9 Q9P286	Q96BZ8
PDB IDs		2F57
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Organelle Organization Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Assembly Mitotic Cell Cycle Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Mitotic Cell Cycle Positive Regulation Of Signal Transduction Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Transferase Activity Cellular Response To Chromate Organelle Transport Along Microtubule Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Death Protein Complex Assembly Regulation Of Lipid Kinase Activity Cell Cycle Process Fc Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Wnt Signaling Pathway Positive Regulation Of DNA Replication Cellular Macromolecular Complex Assembly Regulation Of Signaling Regulation Of T Cell Activation Positive Regulation Of Cell Activation Actin Filament Organization Positive Regulation Of Neuron Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Potential Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Suppression By Virus Of Host Apoptotic Process T Cell Costimulation	Biomineral Tissue Development Negative Regulation Of Viral Release From Host Cell Innate Immune Response Immune Response Negative Regulation Of Viral Transcription Defense Response Regulation Of Viral Release From Host Cell Regulation Of Protein Binding Cell Proliferation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Bone Mineralization Spliceosomal Complex Disassembly Chromosome Localization To Nuclear Envelope Involved In Synapsis
Tagcloud ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Difference) ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Intersection) ?