PAK7 and ARMC7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PAK7	ARMC7
Gene Name		p21 protein (Cdc42/Rac)-activated kinase 7	armadillo repeat containing 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Nucleus Cytoplasm
	Molecular Function	Receptor Signaling Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Proliferation Cell Growth Cell Migration Signal Transduction By Phosphorylation Intracellular Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Axon guidance Activation of Rac Signaling by Robo receptor
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FAM212A FHL3 GCC1 LENG1 LZTS2 PDLIM7 PSMF1 RAC1 SORBS3 TUBGCP4 UXT	23 interactors: ABI2 ABI3 APP C2orf88 CCDC33 CPSF6 CPSF7 EFHC2 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT40 LZTS2 PAK7 RUNDC3A SPATC1L SPERT TCF4 TNFAIP1 TRIM27 TRIM42
Entrez ID		57144	79637
HPRD ID		06423	08649
Ensembl ID		ENSG00000101349	ENSG00000125449
Uniprot IDs		B0AZM9 Q9P286	B4DVA4 Q9H6L4
PDB IDs		2F57
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Organelle Organization Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Assembly Mitotic Cell Cycle Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Mitotic Cell Cycle Positive Regulation Of Signal Transduction Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Transferase Activity Cellular Response To Chromate Organelle Transport Along Microtubule Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Death Protein Complex Assembly Regulation Of Lipid Kinase Activity Cell Cycle Process Fc Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Wnt Signaling Pathway Positive Regulation Of DNA Replication Cellular Macromolecular Complex Assembly Regulation Of Signaling Regulation Of T Cell Activation Positive Regulation Of Cell Activation Actin Filament Organization Positive Regulation Of Neuron Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Potential Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Suppression By Virus Of Host Apoptotic Process T Cell Costimulation	Protein Oligomerization Cellular Component Assembly MRNA 3'-end Processing Stress Fiber Assembly Actin Filament Organization Protein Complex Assembly RNA 3'-end Processing Cytoskeleton Organization Negative Regulation Of Rho Protein Signal Transduction MRNA Polyadenylation RNA Polyadenylation Movement Of Cell Or Subcellular Component Positive Regulation Of Cellular Biosynthetic Process Actin Cytoskeleton Organization Organelle Organization Negative Regulation Of Signal Transduction Positive Regulation Of Neutrophil Differentiation Learning Or Memory Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Actin Filament-based Process Positive Regulation Of DNA Replication Negative Regulation Of Signaling Regulation Of Developmental Growth Cognition Actin Filament Bundle Assembly Locomotion Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nucleobase-containing Compound Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Multicellular Organism Growth Cell Migration Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Tetramerization Maintenance Of DNA Repeat Elements Actomyosin Structure Organization Positive Regulation Of Macromolecule Biosynthetic Process MRNA Processing Cell Motility Regulation Of Signaling Cellular Nitrogen Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Forebrain Development
Tagcloud ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Difference) ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Intersection) ?