PAK5 and DNPEP

Number of citations of the paper that reports this interaction (PubMedID 31219614)
0

Data Source:
BioGRID (enzymatic study)

		PAK5	DNPEP
Description		p21 (RAC1) activated kinase 5	aspartyl aminopeptidase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Nuclear Membrane Synapse	Nucleus Cytoplasm Cytosol Blood Microparticle
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Aminopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Population Proliferation Cellular Response To Starvation Cell Migration Intracellular Signal Transduction Regulation Of MAPK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Proteolysis Peptide Metabolic Process
Pathways		Activation of RAC1 CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOH GTPase cycle
Drugs		Fostamatinib	Glutamic acid
Diseases
GWAS		Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	Height ( 31562340) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Triglyceride levels in HIV infection ( 33109212) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		36 interacting genes: ARHGEF19 ARMC7 ATPAF2 BAD CARD9 CATSPER1 CCDC57 CCNG1 CDC42 CRBN CSNK1D DDX6 DNPEP EMD ENKD1 EXOSC1 FHL3 GCC1 INKA1 LENG1 LNX1 LZTS2 MARK2 MYO15B NTAQ1 PDLIM7 PRPF31 PSMF1 PTPN21 RAC1 RHOJ SORBS3 SRSF11 TSGA10 TUBGCP4 UXT	8 interacting genes: ADAMTSL4 AGT DGCR6 LNX1 MDFI MPP1 PAK5 SAT1
Entrez ID		57144	23549
HPRD ID		06423	09924
Ensembl ID		ENSG00000101349	ENSG00000123992
Uniprot IDs		B0AZM9 Q9P286	B7Z7F0 E5RIA4 E7ETB3 Q9ULA0
PDB IDs		2F57 8C12	4DYO
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cytoskeleton Cytoplasm Wnt Signaling Pathway Microtubule-based Process Microtubule Nucleation Microtubule Cytoskeleton Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Organelle Organization G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cell Projection Assembly Spindle Non-canonical Wnt Signaling Pathway Thioesterase Binding Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Centrosome Establishment Or Maintenance Of Cell Polarity Midbrain Dopaminergic Neuron Differentiation Cellular Component Assembly GTP-dependent Protein Binding Cytoplasmic Ribonucleoprotein Granule Actin Cytoskeleton Organization Plasma Membrane Bounded Cell Projection Assembly Tau-protein Kinase Activity Establishment Of Cell Polarity Regulation Of Stress Fiber Assembly	Positive Regulation Of Angiotensin-activated Signaling Pathway Extracellular Matrix Renin-angiotensin Regulation Of Aldosterone Production Positive Regulation Of Membrane Hyperpolarization Response To Muscle Activity Involved In Regulation Of Muscle Adaptation G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Regulation Of Renal Output By Angiotensin Type 2 Angiotensin Receptor Binding Diamine N-acetyltransferase Activity Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding Pigment Cell Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?