PAK7 and UXT

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PAK7	UXT
Gene Name		p21 protein (Cdc42/Rac)-activated kinase 7	ubiquitously-expressed, prefoldin-like chaperone
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Receptor Signaling Protein Serine/threonine Kinase Activity ATP Binding	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Proliferation Cell Growth Cell Migration Signal Transduction By Phosphorylation Intracellular Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization Transcription, DNA-templated Mitochondrion Transport Along Microtubule Centrosome Organization
Pathways		Axon guidance Activation of Rac Signaling by Robo receptor
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FAM212A FHL3 GCC1 LENG1 LZTS2 PDLIM7 PSMF1 RAC1 SORBS3 TUBGCP4 UXT	19 interactors: APP AR CECR2 GLE1 KRT31 KRT40 KRTAP10-7 KRTAP10-8 LRPPRC LSM1 NOTCH2NL PAK7 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL
Entrez ID		57144	8409
HPRD ID		06423	02209
Ensembl ID		ENSG00000101349	ENSG00000126756
Uniprot IDs		B0AZM9 Q9P286	Q9UBK9
PDB IDs		2F57
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Organelle Organization Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Assembly Mitotic Cell Cycle Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Mitotic Cell Cycle Positive Regulation Of Signal Transduction Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Transferase Activity Cellular Response To Chromate Organelle Transport Along Microtubule Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Death Protein Complex Assembly Regulation Of Lipid Kinase Activity Cell Cycle Process Fc Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Wnt Signaling Pathway Positive Regulation Of DNA Replication Cellular Macromolecular Complex Assembly Regulation Of Signaling Regulation Of T Cell Activation Positive Regulation Of Cell Activation Actin Filament Organization Positive Regulation Of Neuron Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Potential Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Suppression By Virus Of Host Apoptotic Process T Cell Costimulation	Cell Growth Single-organism Behavior Posttranscriptional Regulation Of Gene Expression Locomotory Behavior Behavior Neuron Apoptotic Process Learning Or Memory Negative Regulation Of Integrin Biosynthetic Process Developmental Process Neuron Death Cognition Synaptic Growth At Neuromuscular Junction Positive Regulation Of Progesterone Secretion Negative Regulation Of Mitochondrial RNA Catabolic Process Anatomical Structure Development Collateral Sprouting In Absence Of Injury Positive Regulation Of Integrin Biosynthetic Process Regulation Of Progesterone Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Hair Follicle Cell Proliferation Regulation Of Integrin Biosynthetic Process MRNA Transport Neuron Development Memory Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Steroid Hormone Microtubule-based Transport Programmed Cell Death Regulation Of Protein Stability Skeletal Muscle Tissue Development RNA Transport Learning Notch Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Growth Cytoskeleton-dependent Intracellular Transport Tissue Development Cell Death Death Skeletal Muscle Organ Development RNA Localization Axon Choice Point Recognition Striated Muscle Atrophy Response To Abiotic Stimulus
Tagcloud ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3	angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish
Tagcloud (Difference) ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase putatively rab23 rap2a slc11a1 sod3 tp53i3	angiogenesis attenuates consequent csl developmentally division endogenously evolutionarily impairing indispensable inductions intersegmental isv isvs jkappa mechanistically myriad nicd notch orchestrated rbp repressor rescues shedding spatially temporally tip vessel zebrafish
Tagcloud (Intersection) ?