NAGK and PKM

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NAGK	PKM
Gene Name		N-acetylglucosamine kinase	pyruvate kinase, muscle
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cilium Extracellular Matrix Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	Magnesium Ion Binding Pyruvate Kinase Activity Protein Binding ATP Binding MHC Class II Protein Complex Binding Potassium Ion Binding Poly(A) RNA Binding
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Programmed Cell Death Phosphorylation Small Molecule Metabolic Process
Pathways
Drugs			Pyruvic acid L-Phospholactate 2-Phosphoglycolic Acid 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2\',3\':4,5]pyrrolo[2,3-d]pyridazin-5-one 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	35 interactors: ANXA7 APP ARAF CDK4 CDKN1A EGLN3 EXOSC5 GRB7 HERC1 HIF1A LMO7 LNX1 MDM2 MYOC NAGK NDRG1 NXT2 OLFM2 PAX8 PIN1 POLE2 RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 TERF1 TINF2 TK1 TRIM63 UCHL5 YWHAQ
Entrez ID		55577	5315
HPRD ID		08441	01529
Ensembl ID		ENSG00000124357	ENSG00000067225
Uniprot IDs		C9JEV6 Q9UJ70	B4DNK4 P14618
PDB IDs		2CH5 2CH6	1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG
Enriched GO Terms of Interacting Partners?			Response To Abiotic Stimulus Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process ERBB Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stress Regulation Of Signaling Intestinal Epithelial Cell Maturation Cellular Response To Hypoxia Telomere Maintenance Via Telomere Lengthening Cellular Response To Decreased Oxygen Levels Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Neurotrophin Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Response To Organic Substance Response To Organic Cyclic Compound Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Proteolysis Regulation Of Cell Cycle Response To Hormone Response To Inorganic Substance Response To Steroid Hormone Nervous System Development Regulation Of Cellular Component Organization Cell Maturation Response To Hypoxia Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Phase Transition Skeletal Muscle Adaptation Negative Regulation Of Telomere Maintenance G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?			acutely amplitudes applications aspartate blockade ca1 changing channel clamp coapplication combinations consequence currents heterodimeric hippocampal inside mg2 nmda nr1a nr2a nr2b opening patch patches potentiated potentiation probability sensitivities voltage
Tagcloud (Difference) ?			acutely amplitudes applications aspartate blockade ca1 changing channel clamp coapplication combinations consequence currents heterodimeric hippocampal inside mg2 nmda nr1a nr2a nr2b opening patch patches potentiated potentiation probability sensitivities voltage
Tagcloud (Intersection) ?