NAGK and FGFR1OP

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NAGK	FGFR1OP
Gene Name		N-acetylglucosamine kinase	FGFR1 oncogene partner
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	Protein Tyrosine Kinase Activity Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Organelle Organization Positive Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways			Organelle biogenesis and maintenance Signaling by FGFR in disease Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Signaling by FGFR1 mutants Loss of Nlp from mitotic centrosomes Signaling by FGFR mutants Centrosome maturation Signaling by FGFR1 fusion mutants Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS			Graves' disease ( 21841780) Vitiligo ( 20526339)
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	4 interactors: CEP19 NAGK PPP2R1B VASP
Entrez ID		55577	11116
HPRD ID		08441	10392
Ensembl ID		ENSG00000124357
Uniprot IDs		C9JEV6 Q9UJ70	B4DH64 O95684
PDB IDs		2CH5 2CH6	2D68
Enriched GO Terms of Interacting Partners?			N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process N-acetylneuraminate Metabolic Process
Tagcloud ?			aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Difference) ?			aberrant abl1 balanced bcr chimaeric cloning cmml constitutive constitutively cytological fusion hematopoietic lineage mimic monocytic myelomonocytic myeloproliferative neoplasms q11 q27 remissions ret seem skew sorafenib tk transform translocations v617f
Tagcloud (Intersection) ?