NAGK and DACH1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		NAGK	DACH1
Gene Name		N-acetylglucosamine kinase	dachshund family transcription factor 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity Involved In Preinitiation Complex Assembly RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Protein Binding
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Suckling Behavior Respiratory Gaseous Exchange Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Cell Migration Development Of Primary Female Sexual Characteristics Negative Regulation Of Fibroblast Proliferation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Cell Proliferation Involved In Contact Inhibition
Pathways
Drugs
Diseases
GWAS			Adverse response to lamotrigine and phenytoin ( 22379998) Chronic kidney disease ( 20383146) Longevity ( 20834067) Obsessive-compulsive disorder ( 22889921) Urate levels ( 23263486)
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	18 interactors: AHCYL1 C1orf35 CREBBP EYA1 EYA3 FGF12 JUN NAGK NCOR1 PPIG RNF14 SIN3A SIX1 SMAD3 SMAD4 U2AF2 UBE2I ZCCHC10
Entrez ID		55577	1602
HPRD ID		08441	16031
Ensembl ID		ENSG00000124357	ENSG00000165659
Uniprot IDs		C9JEV6 Q9UJ70	Q9UI36
PDB IDs		2CH5 2CH6	1L8R
Enriched GO Terms of Interacting Partners?			RNA Metabolic Process Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heart Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heart Development Positive Regulation Of Transcription, DNA-templated Ureteric Bud Development Negative Regulation Of Biosynthetic Process Mesonephric Tubule Development Mesonephric Epithelium Development Regulation Of Heart Morphogenesis Mesonephros Development Cellular Metabolic Process Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Secondary Heart Field Cardioblast Proliferation Macromolecule Biosynthetic Process Kidney Epithelium Development Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of DNA-templated Transcription In Response To Stress SMAD Protein Signal Transduction Histone Dephosphorylation Response To Transforming Growth Factor Beta Branching Involved In Ureteric Bud Morphogenesis Outflow Tract Morphogenesis
Tagcloud ?			atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis
Tagcloud (Difference) ?			atlas basal bcl2 call chip conclusionthe considerations depend deregulation focused gata3 introductiongata3 luminal mammary methodsgata3 mutated proper regard representing resultswe seq shared shift signatures special subgroup suppressing thsd4 tumorigenesis
Tagcloud (Intersection) ?