NAGK and SPRED1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NAGK	SPRED1
Gene Name		N-acetylglucosamine kinase	sprouty-related, EVH1 domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Caveola
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	Stem Cell Factor Receptor Binding Protein Binding Protein Kinase Binding Phosphatase Binding Protein Serine/threonine Kinase Inhibitor Activity
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Inactivation Of MAPK Activity Multicellular Organismal Development Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Phosphatase Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Deacetylation
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 23128233) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	11 interactors: CDKN1A DNAJB11 FAM118B KIT NAGK OSGEP PPP1CA RCC1 SUV39H1 TSC22D1 TTC19
Entrez ID		55577	161742
HPRD ID		08441	11601
Ensembl ID		ENSG00000124357	ENSG00000166068
Uniprot IDs		C9JEV6 Q9UJ70	Q7Z699
PDB IDs		2CH5 2CH6	3SYX
Enriched GO Terms of Interacting Partners?			Cell Division Cell Cycle Rhythmic Process Response To Light Stimulus Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Response To Radiation Response To Abiotic Stimulus Regulation Of Circadian Rhythm Positive Regulation Of Protein Kinase Activity Threonylcarbamoyladenosine Biosynthetic Process Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway N-acetylmannosamine Metabolic Process Positive Regulation Of Kinase Activity Mast Cell Differentiation Positive Regulation Of Transferase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Mast Cell Chemotaxis Cellular Response To Erythropoietin N-acetylneuraminate Catabolic Process Response To Growth Factor Digestive System Development Positive Regulation Of Cell Death RNA Modification G1/S Transition Of Mitotic Cell Cycle Threonylcarbamoyladenosine Metabolic Process Intestinal Epithelial Cell Maturation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Catalytic Activity Tube Development Regulation Of Cell Death Cellular Response To Fibroblast Growth Factor Stimulus Melanocyte Migration Histone H3-K9 Dimethylation Positive Regulation Of Protein Phosphorylation Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Ran GTPase Activity Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Tagcloud ?			3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Difference) ?			3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Intersection) ?