NAGK and CDKN2C

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NAGK	CDKN2C
Gene Name		N-acetylglucosamine kinase	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Phosphorylation Oligodendrocyte Differentiation Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways			Cyclin D associated events in G1 Oxidative Stress Induced Senescence G1 Phase Cellular Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Ventricular conduction ( 21076409)
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	27 interactors: AHCYL1 APLP1 ATM ATR CCDC90B CDK4 CDK6 CDKN2A COPS6 DRAP1 GDF9 GOPC LRIF1 LY96 MAPK10 MAPK8 NAGK NHP2L1 NIF3L1 PPP2CA RBM48 REL TCF12 TCF4 TLE1 TP53 UNC119
Entrez ID		55577	1031
HPRD ID		08441	04534
Ensembl ID		ENSG00000124357	ENSG00000123080
Uniprot IDs		C9JEV6 Q9UJ70	P42773 Q6ICV4
PDB IDs		2CH5 2CH6	1BU9 1G3N 1IHB 1MX2 1MX4 1MX6
Enriched GO Terms of Interacting Partners?			Replicative Senescence Regulation Of Gene Expression Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Signal Transduction Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Cycle Arrest Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Process Cell Aging Positive Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Arrest Mitotic Cell Cycle Process RNA Metabolic Process Cell Cycle Negative Regulation Of Growth Regulation Of Intracellular Signal Transduction Response To Radiation Negative Regulation Of Cell Cycle Regulation Of Signal Transduction Signal Transduction Mitotic Cell Cycle JUN Phosphorylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Death Positive Regulation Of Cell Aging Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Signaling Negative Regulation Of Cell Growth Response To Gamma Radiation Regulation Of Signaling Positive Regulation Of Cellular Metabolic Process Response To Light Stimulus Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Apoptotic Process Cell Communication Positive Regulation Of Programmed Cell Death Cellular Metabolic Process Cellular Response To Ionizing Radiation Positive Regulation Of Cell Death
Tagcloud ?			a134c abp allelic ankyrin balb cdk6 cdnas chr congenic d2 dba g232a ifna inbred inefficient ink4c le multigenic mus p15 p16 p18 pctr1 plasmacytoma pristane spretus typed
Tagcloud (Difference) ?			a134c abp allelic ankyrin balb cdk6 cdnas chr congenic d2 dba g232a ifna inbred inefficient ink4c le multigenic mus p15 p16 p18 pctr1 plasmacytoma pristane spretus typed
Tagcloud (Intersection) ?