PKM and NXT2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PKM	NXT2
Gene Name		pyruvate kinase, muscle	nuclear transport factor 2-like export factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cilium Extracellular Matrix Vesicle Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding Pyruvate Kinase Activity Protein Binding ATP Binding MHC Class II Protein Complex Binding Potassium Ion Binding Poly(A) RNA Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Programmed Cell Death Phosphorylation Small Molecule Metabolic Process	Protein Transport MRNA Transport
Pathways
Drugs		Pyruvic acid L-Phospholactate 2-Phosphoglycolic Acid 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2\',3\':4,5]pyrrolo[2,3-d]pyridazin-5-one 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ANXA7 APP ARAF CDK4 CDKN1A EGLN3 EXOSC5 GRB7 HERC1 HIF1A LMO7 LNX1 MDM2 MYOC NAGK NDRG1 NXT2 OLFM2 PAX8 PIN1 POLE2 RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 TERF1 TINF2 TK1 TRIM63 UCHL5 YWHAQ	16 interactors: APP CCDC102B CEP63 GOLGA2 LNX1 NXF1 NXF2 NXF3 PKM PTPN3 REL SRPK1 SRPK2 SSBP3 TRIM23 USP54
Entrez ID		5315	55916
HPRD ID		01529	02264
Ensembl ID		ENSG00000067225	ENSG00000101888
Uniprot IDs		B4DNK4 P14618	Q9NPJ8
PDB IDs		1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process ERBB Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stress Regulation Of Signaling Intestinal Epithelial Cell Maturation Cellular Response To Hypoxia Telomere Maintenance Via Telomere Lengthening Cellular Response To Decreased Oxygen Levels Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Neurotrophin Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Response To Organic Substance Response To Organic Cyclic Compound Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Proteolysis Regulation Of Cell Cycle Response To Hormone Response To Inorganic Substance Response To Steroid Hormone Nervous System Development Regulation Of Cellular Component Organization Cell Maturation Response To Hypoxia Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction Positive Regulation Of Cell Cycle Phase Transition Skeletal Muscle Adaptation Negative Regulation Of Telomere Maintenance G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway	MRNA Export From Nucleus RNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Positive Regulation Of Viral Genome Replication RNA Localization Negative Regulation Of Viral Genome Replication Gene Expression Nucleocytoplasmic Transport Nuclear Transport Nuclear Speck Organization Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Innate Immune Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Anterior Head Development Regulation Of MRNA Processing Regulation Of RNA Splicing Collateral Sprouting In Absence Of Injury MRNA Processing Neural Plate Anterior/posterior Regionalization Liver Regeneration Nucleus Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Membrane Depolarization During Action Potential Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Protein Binding MRNA Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Intracellular Signal Transduction Viral Process Cellular Component Assembly RNA Processing Neuron Remodeling Sperm Chromatin Condensation Immune Response Centriole Replication Positive Regulation Of Interleukin-12 Biosynthetic Process Defense Response Immune System Process Midbrain-hindbrain Boundary Development
Tagcloud ?		acutely amplitudes applications aspartate blockade ca1 changing channel clamp coapplication combinations consequence currents heterodimeric hippocampal inside mg2 nmda nr1a nr2a nr2b opening patch patches potentiated potentiation probability sensitivities voltage
Tagcloud (Difference) ?		acutely amplitudes applications aspartate blockade ca1 changing channel clamp coapplication combinations consequence currents heterodimeric hippocampal inside mg2 nmda nr1a nr2a nr2b opening patch patches potentiated potentiation probability sensitivities voltage
Tagcloud (Intersection) ?