NAGK and MTHFD2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NAGK	MTHFD2
Gene Name		N-acetylglucosamine kinase	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
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Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Extracellular Space Mitochondrion Cytosol
	Molecular Function	Protein Binding ATP Binding N-acylmannosamine Kinase Activity N-acetylglucosamine Kinase Activity	Magnesium Ion Binding Formate-tetrahydrofolate Ligase Activity Methenyltetrahydrofolate Cyclohydrolase Activity Methylenetetrahydrofolate Dehydrogenase (NAD+) Activity Methylenetetrahydrofolate Dehydrogenase (NADP+) Activity Phosphate Ion Binding
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	One-carbon Metabolic Process Folic Acid-containing Compound Biosynthetic Process Tetrahydrofolate Metabolic Process Oxidation-reduction Process
Pathways
Drugs			Tetrahydrofolic acid NADH
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ACTR10 CCDC158 CDKN2C DACH1 DCP2 DYNC1I1 FGFR1OP GNPNAT1 LACTB2 LENG1 LNX1 LSM8 MEOX1 MTHFD2 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 STK16 SYNE4 TCF12 TNNT1 WDR82	1 interactors: NAGK
Entrez ID		55577	10797
HPRD ID		08441	05351
Ensembl ID		ENSG00000124357
Uniprot IDs		C9JEV6 Q9UJ70	P13995
PDB IDs		2CH5 2CH6	1ZN4
Enriched GO Terms of Interacting Partners?			N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process N-acetylneuraminate Metabolic Process N-acetylglucosamine Metabolic Process Amino Sugar Metabolic Process Carbohydrate Phosphorylation Carboxylic Acid Catabolic Process Cellular Carbohydrate Metabolic Process
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