PKM and HERC1

  • Number of citations of the paper that reports this interaction (PMID 12650930)
  • 4
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

PKM

HERC1

Gene Name pyruvate kinase, muscle HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 35 interactors: ANXA7 APP ARAF CDK4 CDKN1A EGLN3 EXOSC5 GRB7 HERC1 HIF1A LMO7 LNX1 MDM2 MYOC NAGK NDRG1 NXT2 OLFM2 PAX8 PIN1 POLE2 RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 TERF1 TINF2 TK1 TRIM63 UCHL5 YWHAQ 7 interactors: BAK1 EP300 LAPTM5 PKM RNF11 SOX9 UBE2D3
Entrez ID 5315 8925
HPRD ID 01529 06894
Ensembl ID ENSG00000067225 ENSG00000103657
Uniprot IDs B4DNK4 P14618 Q15751
PDB IDs 1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acutely  amplitudes  applications  aspartate  blockade  ca1  changing  channel  clamp  coapplication  combinations  consequence  currents  heterodimeric  hippocampal  inside  mg2  nmda  nr1a  nr2a  nr2b  opening  patch  patches  potentiated  potentiation  probability  sensitivities  voltage 
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  fbxw7  frequencies  guide  harboured  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Difference) ?
acutely  amplitudes  applications  aspartate  blockade  ca1  changing  channel  clamp  coapplication  combinations  consequence  currents  heterodimeric  hippocampal  inside  mg2  nmda  nr1a  nr2a  nr2b  opening  patch  patches  potentiated  potentiation  probability  sensitivities  voltage 
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  fbxw7  frequencies  guide  harboured  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Intersection) ?