PPIB and PEX19

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPIB	PEX19
Gene Name		peptidylprolyl isomerase B (cyclophilin B)	peroxisomal biogenesis factor 19
Image
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Macromolecular Complex Melanosome Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Collagen Binding Protein Complex Binding Peptide Binding Poly(A) RNA Binding Unfolded Protein Binding RNA Polymerase Binding	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Extracellular Matrix Organization Positive Regulation Of Multicellular Organism Growth Positive Regulation By Host Of Viral Process Positive Regulation By Host Of Viral Genome Replication Protein Stabilization Bone Development Chaperone-mediated Protein Folding Regulation Of Post-translational Protein Modification	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		Collagen formation Collagen biosynthesis and modifying enzymes	ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APOB ATP12A BANP CAMLG DNM2 HIST3H3 IRF3 MDM2 PEX19 PRL SGTA STAT5A UBQLN1 UBQLN4 VKORC1	32 interactors: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		5479	5824
HPRD ID		00458	02610
Ensembl ID		ENSG00000166794	ENSG00000162735
Uniprot IDs		P23284	P40855
PDB IDs		1CYN 3ICH 3ICI	2W85 2WL8 3AJB 3MK4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Cell Cycle JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Response To Growth Hormone Viral Process Regulation Of Body Fluid Levels Cellular Response To Hormone Stimulus JAK-STAT Cascade Positive Regulation Of Mitotic Cell Cycle Phase Transition Lactation Positive Regulation Of Cell Cycle Phase Transition Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Cycle Negative Regulation Of Lipid Binding Negative Regulation Of Interferon-beta Biosynthetic Process Cellular Response To UV-C Positive Regulation Of Mast Cell Differentiation Cellular Response To Vitamin B1 Regulation Of Developmental Growth Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Receptor Metabolic Process Immune System Process Negative Regulation Of Membrane Tubulation MDA-5 Signaling Pathway Macrophage Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Steroid Metabolic Process Regulation Of Multicellular Organism Growth Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Mast Cell Differentiation Development Of Secondary Male Sexual Characteristics Regulation Of Mitotic Cell Cycle Regulation Of Cytokine Biosynthetic Process Body Fluid Secretion Cellular Response To Lipid Cellular Response To Oxygen Levels Response To Hormone Traversing Start Control Point Of Mitotic Cell Cycle Peroxisome Membrane Biogenesis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Negative Regulation Of Mast Cell Apoptotic Process Response To Vitamin B1 Response To Ether Negative Regulation Of Defense Response To Virus By Host	Peroxisome Organization Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Peroxisomal Membrane Transport Protein Import Peroxisome Membrane Biogenesis Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Protein Import Into Peroxisome Membrane Organelle Organization Protein To Membrane Docking Transmembrane Transport Establishment Of Protein Localization To Organelle Fatty Acid Beta-oxidation Protein Targeting Cellular Lipid Catabolic Process Protein Localization To Organelle Regulation Of Peroxisome Size Lipid Modification Membrane Biogenesis Carboxylic Acid Catabolic Process Protein Import Into Peroxisome Matrix, Docking Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Cytoplasmic Transport Fatty Acid Alpha-oxidation Fatty Acid Metabolic Process Establishment Of Protein Localization Peroxisome Fission Intracellular Transport Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Establishment Of Protein Localization To Membrane Cellular Protein Localization Protein Stabilization Membrane Docking Posttranscriptional Regulation Of Gene Expression Protein Transport Positive Regulation Of Viral Genome Replication Cellular Component Assembly Regulation Of Defense Response To Virus By Host Monocarboxylic Acid Metabolic Process
Tagcloud ?		abeta abundance accompanies ad animal biomarkers cytokines diverse elisa immunostaining isotope key labeling lack lc microglia microglial ms nervous neurodegenerative neuroinflammation pdia3 pdia6 proper proteomic resident serpinh1 silac validation	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Difference) ?		abeta abundance accompanies ad animal biomarkers cytokines diverse elisa immunostaining isotope key labeling lack lc microglia microglial ms nervous neurodegenerative neuroinflammation pdia3 pdia6 proper proteomic resident serpinh1 silac validation	amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Intersection) ?