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PEX19 and SLC25A17
Number of citations of the paper that reports this interaction (PubMedID
10704444
)
54
Data Source:
HPRD
(in vivo, in vitro)
PEX19
SLC25A17
Description
peroxisomal biogenesis factor 19
solute carrier family 25 member 17
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Peroxisome
Peroxisomal Membrane
Cytosol
Membrane
Brush Border Membrane
Protein-containing Complex
Cytoplasm
Peroxisome
Peroxisomal Membrane
Cytosol
Membrane
Molecular Function
Protein Binding
Peroxisome Membrane Targeting Sequence Binding
Peroxisome Membrane Class-1 Targeting Sequence Binding
ATPase Binding
Protein Carrier Chaperone
Adenine Nucleotide Transmembrane Transporter Activity
ATP Transmembrane Transporter Activity
Protein Binding
ADP Transmembrane Transporter Activity
Coenzyme A Transmembrane Transporter Activity
FAD Transmembrane Transporter Activity
Antiporter Activity
FMN Transmembrane Transporter Activity
Protein-folding Chaperone Binding
NAD Transmembrane Transporter Activity
AMP Transmembrane Transporter Activity
Biological Process
Protein Folding
Protein Targeting To Peroxisome
Peroxisome Organization
Peroxisome Membrane Biogenesis
Peroxisome Fission
Protein Import Into Peroxisome Membrane
Protein Stabilization
Establishment Of Protein Localization To Peroxisome
Negative Regulation Of Lipid Binding
Fatty Acid Alpha-oxidation
Fatty Acid Beta-oxidation
ADP Transport
ATP Transport
Fatty Acid Transport
Coenzyme A Transmembrane Transport
FAD Transmembrane Transport
NAD Transmembrane Transport
Transmembrane Transport
AMP Transport
Nucleotide Transmembrane Transport
Pathways
ABC transporters in lipid homeostasis
Class I peroxisomal membrane protein import
Class I peroxisomal membrane protein import
Alpha-oxidation of phytanate
Class I peroxisomal membrane protein import
Drugs
Diseases
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
34002096
)
Bipolar I disorder (
31043756
)
Coffee consumption (
31046077
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
Feeling nervous (
29500382
)
Irritable mood (
29500382
)
Low density lipoprotein cholesterol levels (
29083408
)
Neurociticism (
29500382
)
Refractive error (
32231278
)
Interacting Genes
39 interacting genes:
ABCD1
ABCD2
ABCD3
BCL2L11
CDC25A
CDKN2A
DLG4
EIF1B
F11R
FKBP7
GSKIP
IFNB1
IL23A
IRF3
KIFAP3
NAT8L
OIP5
PEX10
PEX11A
PEX11B
PEX12
PEX13
PEX14
PEX16
PEX26
PEX3
PMP22
PPIB
PSORS1C2
PXMP4
SLC25A17
SLC34A1
SLC61A1
SMAD2
SRPK1
STK3
SUOX
TMEM54
TXN2
2 interacting genes:
MEOX2
PEX19
Entrez ID
5824
10478
HPRD ID
02610
08425
Ensembl ID
ENSG00000162735
ENSG00000100372
Uniprot IDs
A0A0S2Z497
P40855
B4DP73
B4DU97
F6RTR7
O43808
PDB IDs
2W85
2WL8
3AJB
3MK4
5LNF
Enriched GO Terms of Interacting Partners
?
Peroxisome Organization
Peroxisomal Membrane
Peroxisomal Membrane Transport
Peroxisome
Establishment Of Protein Localization To Peroxisome
Protein Import Into Peroxisome Matrix
Protein Import Into Peroxisome Matrix, Receptor Recycling
Protein Unfolding
Intracellular Protein Transmembrane Transport
Protein Import Into Peroxisome Matrix, Substrate Release
Receptor Recycling
Peroxisomal Importomer Complex
Protein Transmembrane Transport
Long-chain Fatty Acid Import Into Peroxisome
Receptor Metabolic Process
Protein Import Into Peroxisome Membrane
Very Long-chain Fatty Acid Catabolic Process
Protein Transmembrane Transporter Activity
Establishment Of Protein Localization To Organelle
Fatty Acid Oxidation
Fatty Acid Catabolic Process
Protein Localization To Organelle
Lipid Oxidation
Cellular Localization
Fatty Acyl-CoA Hydrolase Activity
Organophosphate Ester Transmembrane Transporter Activity
Nucleobase-containing Compound Transmembrane Transporter Activity
Cellular Response To Reactive Oxygen Species
Long-chain Fatty Acid Transmembrane Transporter Activity
Fatty Acid Beta-oxidation
Intracellular Transport
Protein Monoubiquitination
Organelle Organization
Sulfur Compound Transmembrane Transporter Activity
Amide Transmembrane Transporter Activity
Regulation Of Peroxisome Size
Peroxisome Membrane Biogenesis
Lipid Modification
Intracellular Protein Transport
Transmembrane Transport
Protein Import Into Peroxisome Matrix, Translocation
Protein Import Into Peroxisome Matrix, Docking
Response To Reactive Oxygen Species
Fatty Acid Transport
Protein-containing Complex
ATPase-coupled Transmembrane Transporter Activity
Protein To Membrane Docking
Very Long-chain Fatty Acid Metabolic Process
Intracellular Lipid Transport
Protein Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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