PPIB

Description		peptidylprolyl isomerase B
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Collagen Binding Cyclosporin A Binding Isomerase Activity Unfolded Protein Binding RNA Polymerase Binding
	Biological Process	Protein Folding Neutrophil Chemotaxis Positive Regulation Of Multicellular Organism Growth Host-mediated Activation Of Viral Process Host-mediated Activation Of Viral Genome Replication Protein Stabilization Bone Development Regulation Of Post-translational Protein Modification
Pathways		Collagen biosynthesis and modifying enzymes SARS-CoV-1 activates/modulates innate immune responses
Drugs		Proline 1,4-Dithiothreitol
Diseases		Osteogenesis imperfecta
GWAS
Novel Interacting Genes		1 novel interacting genes: SMAD6
Interacting Genes		24 interacting genes: APOB ATP12A BANP CAMLG CEBPA DNM2 ESR1 GLP1R H3-4 HSPA6 IRF3 MDM2 PEX19 PRH1 PRL SGTA SGTB STAT5A TP53 TRDN UBQLN1 UBQLN2 UBQLN4 VKORC1
Entrez ID		5479
HPRD ID		00458
Ensembl ID		ENSG00000166794
Uniprot IDs		P23284
PDB IDs		1CYN 3ICH 3ICI 8K0F 8K0I 8K0M 8K17 8KC9
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Identical Protein Binding TRC Complex Positive Regulation Of ERAD Pathway Regulation Of MiRNA Transcription Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Regulation Of ERAD Pathway Protein-containing Complex Regulation Of MiRNA Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Response To Actinomycin D Cellular Response To UV-C Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Establishment Of Protein Localization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Leukocyte Apoptotic Process Negative Regulation Of Proteolysis Autophagy Positive Regulation Of MiRNA Transcription Cellular Response To Antibiotic Regulation Of Cellular Response To Stress Response To Estrogen Positive Regulation Of MiRNA Metabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Macromolecule Metabolic Process Response To Stress Cardiac Septum Morphogenesis Regulation Of Macroautophagy Response To UV-C Establishment Of Protein Localization To Membrane Response To Hormone Autophagosome Tail-anchored Membrane Protein Insertion Into ER Membrane Cellular Response To Stress Enzyme Binding Myeloid Cell Apoptotic Process Cellular Response To Estrogen Stimulus Cytokine-mediated Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Response To Endoplasmic Reticulum Stress ERAD Pathway
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