JAK3 and STAM

  • Number of citations of the paper that reports this interaction (PMID 10899310)
  • 17
  • Data Source:
  • HPRD (in vitro, in vivo)

JAK3

STAM

Gene Name Janus kinase 3 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 19 interactors: ARRB1 CLTC HGS JAK1 JAK2 JAK3 PJA1 PPP1CA PPP1CC RFFL STAMBP TIMM8A TRIM54 TRIM55 TRIM63 UBC USP15 USP28 USP8
Entrez ID 3718 8027
HPRD ID 02547 03542
Ensembl ID ENSG00000105639 ENSG00000136738
Uniprot IDs P52333 Q92783
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 2L0A 3F1I 3LDZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
adaptor  cloned  coil  coiled  colony  conserved  counteracts  counterpart  deleted  exogenous  granulocyte  hepatocyte  hrs  inducible  introduction  kda  lost  macrophage  molecularly  molecule  mutual  phosphotyrosine  rapidly  stimulating  stimulation  suppressive  transducing  transduction  tyrosine 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6 
adaptor  cloned  coil  coiled  colony  conserved  counteracts  counterpart  deleted  exogenous  granulocyte  hepatocyte  hrs  inducible  introduction  kda  lost  macrophage  molecularly  mutual  phosphotyrosine  rapidly  stimulating  stimulation  suppressive  transducing  tyrosine 
Tagcloud (Intersection) ?
molecule  transduction