JAK3 and CXCR4

  • Number of citations of the paper that reports this interaction (PMID 10506573)
  • 70
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

JAK3

CXCR4

Gene Name Janus kinase 3 chemokine (C-X-C motif) receptor 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 32 interactors: ADRBK2 ARRB2 ATP13A2 CCR5 CD4 CTSG CXCL12 DPP4 ELANE GNA13 GNAI1 HLA-C HSPA8 ITCH JAK1 JAK2 JAK3 MYBL2 MYH9 PTK2 PTPN11 PTPN6 PTPRC SDC4 SOCS1 SOCS3 STAT1 STAT2 STAT3 STAT5B USP14 VAV1
Entrez ID 3718 7852
HPRD ID 02547 01217
Ensembl ID ENSG00000105639 ENSG00000121966
Uniprot IDs P52333 P61073
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 2K03 2K04 2K05 3ODU 3OE0 3OE6 3OE8 3OE9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
capture  ccr1  ccr2  ccr5  ccr7  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Intersection) ?
cd40