JAK3 and ERBB3

  • Number of citations of the paper that reports this interaction (PMID 16273093)
  • 170
  • Data Source:
  • BioGRID (unspecified method)

JAK3

ERBB3

Gene Name Janus kinase 3 erb-b2 receptor tyrosine kinase 3
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 66 interactors: ABL1 ABL2 AGTR2 BCAR3 CD82 CDK5 CHN2 CRK CRKL DAB1 DAPP1 EGF EGFR EGR1 ERBB2 ERBB4 FER FGFR1 FLNA FLYWCH1 GRB2 GRB7 HCK HDAC6 IL6ST ITK JAK2 JAK3 MUC1 NCK1 NCK2 NEDD4 NRG1 NRG2 ODF2L PA2G4 PIK3R1 PIK3R2 PIK3R3 PLCG1 PTGES3 PTK2 PTK2B PTK6 RASA1 RASA4 RGS4 RIN1 RNF41 RPN1 SH2B3 SH2D1A SHC1 SHC3 SOS1 SRC SYK TNS2 TNS3 TNS4 TXK VAV1 VAV2 VAV3 ZAP70 ZNF207
Entrez ID 3718 2065
HPRD ID 02547 01820
Ensembl ID ENSG00000105639 ENSG00000065361
Uniprot IDs P52333 P21860
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 1M6B 2L9U 3KEX 3LMG 3P11 4LEO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
acquire  alteration  associate  cascades  concurrent  dependence  egf  enhancing  latent  mapk  mediators  p42  p44  phosphotyrosine  potentiates  potentiating  predicts  prime  priming  progestin  progestins  r5020  shc  shift  stat5  steroid  switches  synergistically  waf1 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
acquire  alteration  associate  cascades  concurrent  dependence  egf  enhancing  latent  mapk  p42  p44  phosphotyrosine  potentiates  potentiating  predicts  prime  priming  progestin  progestins  r5020  shc  shift  stat5  steroid  switches  synergistically  waf1 
Tagcloud (Intersection) ?
mediators