JAK3 and JAK1

  • Number of citations of the paper that reports this interaction (PMID 9553136)
  • 11
  • Data Source:
  • HPRD (in vitro, in vivo)

JAK3

JAK1

Gene Name Janus kinase 3 Janus kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2
Entrez ID 3718 3716
HPRD ID 02547 00992
Ensembl ID ENSG00000105639 ENSG00000162434
Uniprot IDs P52333 P23458
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Intersection) ?