JAK3 and PTPN2

  • Number of citations of the paper that reports this interaction (PMID 11909529)
  • 58
  • Data Source:
  • HPRD (in vitro, in vivo)

JAK3

PTPN2

Gene Name Janus kinase 3 protein tyrosine phosphatase, non-receptor type 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 18 interactors: CDK1 CDK2 CDK5 EGFR FKBP4 GHR INSR ITGA1 JAK1 JAK3 KPNB1 PDGFRB SHC1 SRC STAT1 STAT3 STAT5A STAT5B
Entrez ID 3718 5771
HPRD ID 02547 06768
Ensembl ID ENSG00000105639 ENSG00000175354
Uniprot IDs P52333 A8K3N4 K7ENG3 K7EQG9 P17706 Q59F91
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 1L8K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
Tagcloud (Intersection) ?