STAM and STAMBP

Number of citations of the paper that reports this interaction (PubMedID 16730941)
0

Data Source:
HPRD (two hybrid, in vivo)

		STAM	STAMBP
Description		signal transducing adaptor molecule	STAM binding protein
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane ESCRT-0 Complex	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding	Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Protein Domain Specific Binding Metal Ion Binding K63-linked Deubiquitinase Activity Deubiquitinase Activity Metal-dependent Deubiquitinase Activity
	Biological Process	Signal Transduction Protein Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Fission Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly	Mitotic Cytokinesis Proteolysis Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Protein Deubiquitination Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein K63-linked Deubiquitination Hippocampal Neuron Apoptotic Process Negative Regulation Of Hippocampal Neuron Apoptotic Process
Pathways		EGFR downregulation Metalloprotease DUBs Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT)	Metalloprotease DUBs
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Bell's palsy ( 33602968) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944 33031748)
Interacting Genes		21 interacting genes: HGS JAK1 JAK2 JAK3 MAP3K1 PJA1 PMEPA1 PPP1CA PPP1CC RFFL RIPK4 SNCA STAMBP TIMM8A TRIM54 TRIM55 TRIM63 USP15 USP28 USP8 WWP2	51 interacting genes: ALAS1 AMN APOBEC3A ATG14 BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 DSCR9 EGFR EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 MLKL NLRP7 NTPCR PJA1 RBM11 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S ULK1 USP21 USP28 VHL
Entrez ID		8027	10617
HPRD ID		03542	05877
Ensembl ID		ENSG00000136738	ENSG00000124356
Uniprot IDs		B4DZT2 Q92783	A0A140VK54 A0A804HIF8 A0A804HII8 A0A804HJ64 O95630
PDB IDs		2L0A 3F1I 3LDZ	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?		Protein Modification Process Protein Metabolic Process Post-translational Protein Modification Growth Hormone Receptor Binding Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT Endosome Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Deubiquitinase Activity Ubiquitin Protein Ligase Activity Protein Deubiquitination Cytoplasm Protein Modification By Small Protein Removal Regulation Of Signal Transduction Metal Ion Binding Macromolecule Metabolic Process Transferase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signal Transduction Interleukin-4-mediated Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Signal Transduction PTW/PP1 Phosphatase Complex Interleukin-9-mediated Signaling Pathway Interleukin-7-mediated Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Extrinsic Component Of Plasma Membrane Interleukin-15-mediated Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Cytosol Interleukin-2-mediated Signaling Pathway Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Type II Interferon-mediated Signaling Pathway Protein Domain Specific Binding Interleukin-6-mediated Signaling Pathway Postsynapse Cysteine-type Deubiquitinase Activity K63-linked Deubiquitinase Activity Protein Phosphatase Binding K48-linked Deubiquitinase Activity Positive Regulation Of Homotypic Cell-cell Adhesion Cytoplasmic Side Of Plasma Membrane Protein Kinase Activity Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding	ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Organization Multivesicular Body Assembly Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Late Endosome To Vacuole Transport Lysosomal Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Kinetochore Microtubule Autophagosome Membrane Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Regulation Of Mitotic Spindle Organization Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Endosome Organization Regulation Of Spindle Assembly Autophagy Cytokinetic Process Protein-containing Complex Disassembly Endosomal Transport Multivesicular Body Mitotic Metaphase Chromosome Alignment Biological Process Involved In Interaction With Host Nuclear Membrane Organization Vacuolar Transport Vacuole Organization Metaphase Chromosome Alignment Membrane Assembly Endosome Macroautophagy Regulation Of Microtubule Cytoskeleton Organization Chromosome Localization Lysosomal Transport Regulation Of Centrosome Duplication Nuclear Pore Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Nucleus Organization
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