JAK3 and KIT

  • Number of citations of the paper that reports this interaction (PMID 17554063)
  • 3
  • Data Source:
  • BioGRID (enzymatic study)

JAK3

KIT

Gene Name Janus kinase 3 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ALK APOA1 CD247 CD40 CD81 CDK1 CXCR4 ERBB3 FES GTF2B IKBKG IL2RB IL2RG IL4R IL7R INPP5D IRS1 IRS2 JAK1 JAK2 KHDRBS1 KIT LCK PIK3R1 PRMT5 PTK2B PTPN2 PTPN6 PTPRC SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT3 STAT5A STAT5B TIAF1 UHRF2 VIL1 56 interactors: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B TEC YES1
Entrez ID 3718 3815
HPRD ID 02547 01287
Ensembl ID ENSG00000105639 ENSG00000157404
Uniprot IDs P52333 P10721
PDB IDs 1YVJ 3LXK 3LXL 3PJC 3ZC6 4HVD 4HVG 4HVH 4HVI 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2VIF 3G0E 3G0F 4HVS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf  traf2  traf3  traf5  traf6  transduction 
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
Tagcloud (Intersection) ?