PTPN2 and STAT1

  • Number of citations of the paper that reports this interaction (PMID 12138178)
  • 105
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

PTPN2

STAT1

Gene Name protein tyrosine phosphatase, non-receptor type 2 signal transducer and activator of transcription 1, 91kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 18 interactors: CDK1 CDK2 CDK5 EGFR FKBP4 GHR INSR ITGA1 JAK1 JAK3 KPNB1 PDGFRB SHC1 SRC STAT1 STAT3 STAT5A STAT5B 103 interactors: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DOT1L DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 ERBB2 FADD FANCC FGFR3 FGFR4 FLT1 FOS FYN GFAP GNB2L1 GTF2I HADH HLA-B HSF1 HSP90AB1 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTBN1 SRC STAT2 STAT3 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBC UBE2I VDR XPO1 ZNF467
Entrez ID 5771 6772
HPRD ID 06768 02777
Ensembl ID ENSG00000175354 ENSG00000115415
Uniprot IDs A8K3N4 K7ENG3 K7EQG9 P17706 Q59F91 J3KPM9 P42224
PDB IDs 1L8K 1BF5 1YVL 2KA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Intersection) ?