PTPN2 and JAK1

  • Number of citations of the paper that reports this interaction (PMID 11909529)
  • 58
  • Data Source:
  • HPRD (in vitro, in vivo)

PTPN2

JAK1

Gene Name protein tyrosine phosphatase, non-receptor type 2 Janus kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 18 interactors: CDK1 CDK2 CDK5 EGFR FKBP4 GHR INSR ITGA1 JAK1 JAK3 KPNB1 PDGFRB SHC1 SRC STAT1 STAT3 STAT5A STAT5B 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2
Entrez ID 5771 3716
HPRD ID 06768 00992
Ensembl ID ENSG00000175354 ENSG00000162434
Uniprot IDs A8K3N4 K7ENG3 K7EQG9 P17706 Q59F91 P23458
PDB IDs 1L8K 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01
Enriched GO Terms of Interacting Partners?
Tagcloud ?
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Difference) ?
6alpha  acidic  astrocytes  astroglial  atf6alpha  ciliary  cntf  deactivation  dissect  fibrillary  gfap  glia  glial  infarct  lif  master  mcao  neurotrophic  peri  phenylbutyrate  protein78  scar  stressors  tc  thapsigargin  transducer  tunicamycin  unfolded 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Intersection) ?