KIT and BTK

  • Number of citations of the paper that reports this interaction (PMID 15007095)
  • 9
  • Data Source:
  • HPRD (in vivo)

KIT

BTK

Gene Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog Bruton agammaglobulinemia tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B TEC YES1 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2
Entrez ID 3815 695
HPRD ID 01287 02248
Ensembl ID ENSG00000157404 ENSG00000010671
Uniprot IDs P10721 Q06187 Q5JY90
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2VIF 3G0E 3G0F 4HVS 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
Tagcloud (Difference) ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  cytokines  immunomagnetic  leukemic  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
adhesion  allergic  appear  asthma  compares  contrasts  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  hematopoiesis  heterodimer  jak  lyn  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
Tagcloud (Intersection) ?
csf  granulocyte  macrophage