KIT and CRK

  • Number of citations of the paper that reports this interaction (PMID 9233773)
  • 31
  • Data Source:
  • BioGRID (two hybrid)
  • HPRD (in vitro, in vivo)

KIT

CRK

Gene Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog v-crk avian sarcoma virus CT10 oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 56 interactors: ABL1 BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF2RA CSF2RB DOK1 EPOR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK IL7R INPP5D JAK2 JAK3 KITLG LCK LYN MATK MPDZ PIK3CG PIK3R1 PIK3R2 PLCE1 PLCG1 PRKCA PRKCB PTPN11 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SOCS1 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B TEC YES1 84 interactors: ABL1 ABL2 ARHGAP17 ARHGAP32 ASAP1 ATXN1 AVIL BCAR1 BCR BUB1 CBL CBLC CRKL DAB1 DOCK1 DOCK3 DOK1 DOK4 DPPA4 EFS EGFR EPHA3 EPHB2 EPHB3 EPHB6 EPS15 ERBB2 ERBB3 ERBB4 FAM154A FASLG FGFR1 FLT1 FRS2 FYN GAB1 GRB2 IGF1R INSR IRS1 IRS2 IRS4 KDR KHDRBS1 KIT MAP4K1 MAP4K5 MAPK4 MAPK8 MICAL1 NCK1 NEDD9 NTRK1 PDGFRA PDGFRB PIK3R1 PLSCR1 POT1 PPFIBP2 PPP1CA PSMC6 PTK2 PTK2B PTPN1 PTPN4 PXN RAPGEF1 REPS1 RET SH3BP1 SHB SHC1 SOCS1 SOS1 SPRR2A STAT5A STAT5B SYN1 TERF2IP VAV1 WASF1 WEE1 XPO1 ZAP70
Entrez ID 3815 1398
HPRD ID 01287 01267
Ensembl ID ENSG00000157404 ENSG00000167193
Uniprot IDs P10721 L7RT18 P46108
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2VIF 3G0E 3G0F 4HVS 1JU5 2DVJ 2EYV 2EYW 2EYX 2EYY 2EYZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
abundantly  adhesions  arises  associating  carboxy  cas  conferring  connect  coordinating  dim1p  efs  encompassed  encompasses  fyn  hef1  identifies  interactor  localize  multidomain  oncoproteins  p105  p115  p130  p55  sh3  sin  spindle  sum  unexpectedly 
Tagcloud (Difference) ?
advantage  blast  blasts  cd34  clonal  clusters  colonies  continuously  csf  cytokines  granulocyte  immunomagnetic  leukemic  macrophage  microspheres  ng  physiologic  progenitor  purified  rg  rgm  ril  rm  rscf  saturating  scf  subdivided  supported  undifferentiated 
abundantly  adhesions  arises  associating  carboxy  cas  conferring  connect  coordinating  dim1p  efs  encompassed  encompasses  fyn  hef1  identifies  interactor  localize  multidomain  oncoproteins  p105  p115  p130  p55  sh3  sin  spindle  sum  unexpectedly 
Tagcloud (Intersection) ?